The United States recorded nearly 80,000 new coronavirus infections Thursday and 1,000 deaths from COVID-19. Michigan remains the hardest-hit state, but new hot spots are emerging in the Northeast, Texas and parts of the Upper Midwest.

In North Carolina, health officials shut down a mass vaccination site Thursday after several patients had immediate adverse reactions to shots of Johnson & Johnson’s COVID-19 vaccine. This follows similar reports of nausea and dizziness in people who received J&J doses in Colorado a day earlier.

Johnson & Johnson said Thursday it will drastically reduce its deliveries of its vaccine around the U.S. next week, after one of its contractors, Emergent BioSolutions, said 15 million doses at a Baltimore plant were contaminated and needed to be thrown out. The White House has since ordered Johnson & Johnson to take charge of the plant. One in four U.S. adults is now fully vaccinated against COVID-19.