Acclaimed street artist Praxis is taking PETA’s campaign to end cruel, wasteful experiments on animals to the streets of SoHo, where he’s currently painting a massive mural that gives a glimpse into how monkeys suffer in laboratories, where they’re tormented, mutilated, poisoned, held in solitary confinement—often for more than a decade—and then killed.

When:    See the artist painting the mural in real time at 2 p.m. on Friday, October 14

Where:    188 Lafayette St. (between Broome and Grand streets), New York

Praxis and PETA are demanding that the National Institutes of Health (NIH) shut down the seven national primate research centers, which have received billions of taxpayer dollars—and killed tens of thousands of monkeys—yet have failed to deliver effective vaccines to prevent HIV, malaria, tuberculosis, Ebola, and other diseases.

“This is a larger-than-life look at the oppression and exploitation of monkeys occurring right now in taxpayer-funded laboratories,” says PETA Senior Vice President Kathy Guillermo. “PETA and Praxis invite everyone to join us in telling the government to shut down these cruel laboratories and shift to modern research methods that will actually help human patients.”

PETA is calling on NIH to adopt the Research Modernization Deal, which provides a strategy for phasing out unreliable experiments on animals in favor of cutting-edge, human-relevant, animal-free research methods.

Praxis’ artwork also appears on provocative posters throughout the neighborhood.

PETA—whose motto reads, in part, that “animals are not ours to experiment on”—opposes speciesism, a human-supremacist worldview. For more information, please visit PETA.org or follow the group on Twitter, Facebook, or Instagram.