After days of mutual threats, Israel launched an unprecedented series of strikes on Iranian soil early on Friday, targeting Iranian nuclear sites, airports, top military leaders, and nuclear scientists in several locations, including the Iranian capital, Tehran.

At around 3:00 a.m. local time, Iranian news agencies reported several explosions in Tehran, while the Israeli Defense Minister, Israel Katz, declared that Israel had “conducted a preemptive strike against Iran.” Later, Iranian news agency Irna reported that the Israeli strikes had targeted and killed the commander-in-chief of the Iranian Revolutionary Guard, Hussein Salami, as well as the chief of staff of the Iranian armed forces, the head of the revolutionary guard’s Khatem al-Anbiya military complex, and six Iranian nuclear scientists.

The attack also targeted the Iranian Natanz nuclear facility in the center of the country, as well as other nuclear and military facilities in the west. Later in the morning, new Israeli strikes targeted the Tibriz Airport in the north.

Iran’s supreme leader, Ali Khamenei, stated on Friday, following the Israeli attack, that Israel will receive a “hard punishment.” Khamenei also announced the appointment of replacements for the slain military leaders. 

Meanwhile, the Jamqaran mosque in the Islamic holy city of Qom raised the red flag, a Shiite tradition symbolizing coming vengeance. The red flag has been previously raised at Jamqaran before the Iranian response to the assassinations of Quds force general Qasem Suleimani in 2020 and Hamas leader Ismail Haniyeh in 2024. 

Meanwhile, Iranian Foreign Minister Abbas Aragchi urged the International Atomic Energy Agency (IAEA) to condemn the Israeli attack.

Israeli military sources later reported that Iran had launched around 100 attack drones toward Israel and that its air defense systems intercepted them above neighboring countries. However, the spokesperson of the Israeli army said in a press statement that Israel was expecting a larger Iranian retaliation, and that the escalation would last for several days, urging Israelis to remain indoors pending further instructions.

The lead-up: U.S.-Iran nuclear talks

The Israeli attack came after five rounds of Iranian negotiations with the U.S. over Iran’s nuclear program in Oman, and two days away from a sixth round scheduled for Sunday. In recent days, the rhetoric between Iran, the U.S., and Israel has escalated as U.S. President Trump repeated that his confidence in reaching a deal with Iran was diminishing. 

The crucial point of difference in the nuclear talks has been U.S. insistence that Iran should not enrich uranium on its soil for its civil nuclear purposes, which Iran considers a non-starter, insisting on maintaining its enrichment capacity.

Earlier in May, CNN announced that the U.S. had gathered intelligence about Israeli preparations for a strike against Iran, while nuclear talks between Iran and the U.S. were ongoing. This came several days after Trump’s envoy to the Middle East, Steve Witkoff, announced that the U.S. “will not allow Iran to enrich uranium.” 

Last Monday, Iran announced that its intelligence services had obtained thousands of secret Israeli nuclear documents and threatened to reveal their contents.

The lead-up to the attack also saw the repatriation of several U.S. diplomats from the Middle East last Wednesday, including the U.S. embassy in Iraq. The following day, the IAEA announced that Iran was in breach of its nuclear non-proliferation obligations. 

Internally, Israel’s decision to attack Iran came in a delicate political moment, following the voting by the Israeli Knesset on a bill to dissolve itself, supported by the Israeli opposition and Orthodox Haredi parties. The motion passed in its first reading and had two more readings to go before taking effect. Had it been passed, the adopted bill would have forced early elections and put an end to the current government coalition led by Israeli Prime Minister Benjamin Netanyahu.

Although internal pressure on Netanyahu is unprecedented, it comes at a time when the Knesset is due to go into summer recess in the coming weeks, and will be back in session only in autumn. The state of emergency created by attacking Iran will therefore delay the legal process to dissolve the Knesset, possibly saving Netanyahu’s coalition. 

Already on Friday, several Knesset members who voted in favor of the motion to dissolve the Knesset voiced their support for Netanyahu’s decision to attack Iran.

The Knesset vote came after voices have multiplied in calling for the cessation of Israel’s offensive in Gaza, with some ministers within Netanyahu’s government joining the calls.

Internationally, pressure also continues to mount on Israel to end its onslaught on Gaza, especially after its interception of the Madleen aid boat in international waters last week and its ongoing detainment of several of its passengers, including French European parliament member Rima Hassan. 

Pressure also mounted last week after five European countries, including the UK, imposed sanctions on Israeli far-right ministers Bezalel Smotrich and Itamar Ben-Gvir.

What the attack on Iran means for Palestinians

In Gaza, the humanitarian situation in Gaza has deteriorated even further after two weeks of food rations being distributed through the Israeli-backed and U.S.-controlled Gaza Humanitarian Foundation (GHF), the controversial organization tasked with distributing aid to Palestinians instead of the UN. Israeli forces have committed several aid massacres against starving Gazans at the GHF’s distribution points in southern and central Gaza. The massacres have seen the killing of dozens of civilians at GHF sites on a near-daily basis, often after the Israeli army has opened fire on desperate crowds of civilians.

On Thursday, the UN General Assembly adopted a resolution to end the war in Gaza by an overwhelming majority. The vote came almost ten days after the U.S. vetoed a similar resolution at the UN Security Council, sparking widespread criticism.

The international sense of alarm created by the Israeli-made humanitarian crisis in Gaza could only be topped by the new alarming situation created by the Israeli attack on Iran. The expectations of an Iranian response and the risk of an all-out regional war in the Middle East have raised global alarm among world leaders, including British Prime Minister Keir Starmer and French President Emmanuel Macron, who called for “de-escalation” on Friday.

Meanwhile, Israel’s ongoing offensive on Palestinians in the West Bank, which has already been shaded by regional developments, continues to move further away from the spotlight. Immediately following its attack on Iran, Israel imposed a total closure on the West Bank, closing a number of checkpoints and restricting the circulation of Palestinians. Israel also closed the Allenby Bridge crossing to Jordan, the only way out of the country for West Bank Palestinians.

In recent weeks, Israel ramped up its offensive on the West Bank, adopting new decisions that allowed it to confiscate more Palestinian land and announcing the building of 22 new settlements. This has come amid a widening military crackdown on West Bank towns and cities, most recently when Israeli forces killed two Palestinian brothers and wounded thirty Palestinians in Nablus during a 28-hour raid last Tuesday. Meanwhile, its forces continue to occupy the Jenin and Tulkarem refugee camps, demolishing more homes in the camps and preventing the return of its over 40,000 expelled residents.

This post was originally published on The Real News Network.