Category: Cell-Based News

  • salmon
    3 Mins Read

    When it comes to seafood alternatives, the choices are limited. Dutch start-up Upstream Foods aims to change that by cultivating fat from salmon cells for the plant-based seafood market.

    The alternative seafood sector has seen significant growth in the U.S., with both dollar and unit sales experiencing a 53 percent increase last year, according to the Good Food Institute (GFI). This upward trend is expected to continue. But to truly appeal to mainstream consumers, alternative seafood needs to elevate its quality.

    As consumer demand for sustainable alternatives continues to grow, companies like Upstream Foods are striving to meet the challenge and provide high-quality options. Upstream Foods’ innovative approach to cultivating salmon cell fat for use in plant-based seafood aims to revolutionize the industry.

    ‘Next level fat’

    Kianti Figler, founder and CEO of Upstream Foods, emphasized the need for improved product quality during her speech at F&A Next, an event hosted by Rabobank, Wageningen University & Research, Anterra Capital, and StartLife. She acknowledged that the current offerings do not yet match the taste and quality expected by consumers, Food Navigator reports.

    Plantish vegan salmon | Courtesy

    “When we’re talking about taste, we’re talking about fat,” she said at the event. “To take plant-based seafood to the next level, we need next level fat.”

    According to recent TURF analyses, the main reasons consumers would choose plant-based seafood are flavor (78 percent), the potential to reduce overfishing (7 percent), omega-3 content (3 percent), lack of bones (1 percent), and contribution to reducing plastic waste (1 percent). GFI suggests that once consumers have a positive impression of alternative seafood flavors, messaging focused on these additional benefits can make the products more appealing.

    Figler agrees with this approach and believes that taste and fat are closely linked. Upstream Foods’ solution involves cultivating fish fat from salmon cells through cellular agriculture. The company develops a proprietary cell line from salmon cells, cultivates them in a bioreactor, and then combines the fat with a plant-based matrix.

    Scaling up

    Upstream Foods is currently optimizing its salmon cell line and establishing its process at a lab-scale. The company foresees the main challenge in scaling up will be reducing production costs.

    Figler acknowledges that cost efficiency is a significant hurdle faced by the entire industry, as the infrastructure has primarily been designed for the pharmaceutical sector, lacking incentives for ingredient cost reduction.

    fish
    Courtesy Martin Widenka via Unsplash

    “Making this entire process cost efficient is, I think, the biggest challenge we’re all facing,” Figler said.

    While Figler expressed a desire to enter the European market first, she noted that the time-consuming process of submitting a Novel Foods application to the European Food Safety Authority (EFSA) might not be feasible for a start-up. Instead, Upstream Foods plans to focus on the U.S. market, aiming to scale its process and file for regulatory approval within four years.

    The road to market entry involves developing a proof of concept with global plant-based seafood players, followed by raising €3 million in seed funding. Upstream Foods plans to scale its process to 30L and then 100L, with further increases in scale before seeking regulatory approval in the U.S.

    While Europe may not be the initial market for Upstream Foods due to the challenges associated with EFSA approval, the company remains optimistic about the future of plant-based seafood and the potential to offer quality products that satisfy consumers’ taste preferences while delivering health benefits and affordability.

    The post Upstream Foods Says Cultivated Fat Will Help Plant-Based Seafood Market Surge first appeared on Green Queen.

    The post Upstream Foods Says Cultivated Fat Will Help Plant-Based Seafood Market Surge appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 4 Mins Read

    From improvements to yield, cost savings, and increasing climate resilience, there is much to change about the way we make food, especially given how much impact climate change will have on global supply chains, particularly in Southeast Asia.

    I found it fascinating to watch eight innovative agri-tech start-ups from the United Kingdom give their grand pitch in Singapore, a country that has little agricultural activity, at the Gateway to Asia Technology Showcase as part of Innovate UK Global Incubator Programme, and each of them left me feeling inspired and hopeful about the future of food. Here’s everything you need to know about each company and its mission.

    OlaTek

    Did you know that approximately 30% of all fish does not end up on our plates, but rather in our ocean, as waste? Further, this waste results in the contamination of marine ecosystems. Given how much we fish (and how much fish we consume), that’s a significant waste stream that can be upcycled. This is why start-ups like OlaTek are turning fish waste into something valuable- the team is currently working on a proof-of-concept whereby no fish waste gets sent back into the ocean. Even though they’re only just starting with lubricants for the F&B industry, they are expanding to other use cases. 

    Koolmill

    If you’ve heard about Software-as-a-Service, meet Machinery-as-a-Service. Koolmill aims to develop rice harvesting technologies that reduce grain loss and improve efficiency during production by creating a gentler way to process rice. The company’s mission is to help us use what we have more effectively and their motto, which left me giggling, is “be nice to rice”.

    Straw Innovations

    Southeast Asians love their rice, and like Koolmil, this company also wants to transform the industry. When rice gets harvested, its stems and leaves (also known as the straw) get left behind because it’s tricky to collect them, and they end up rotting or burning. This process releases methane, a potent greenhouse gas (and a key reason for rice’s hefty environmental footprint). Straw Innovations is developing a rice AND straw harvester, allowing you to leave less of a stubble (!), a cleaner way to shave the world (excuse the pun).

    Fotenix

    This company says it wants to create the metaverse of agriculture. With a slew of cool videos showing how they use small cameras to take pictures of plants growing in high-tech farming environments, this company uses these pictures to develop digital twins that can give you an amazing array of insights. Imagine being able to see when a plant gets diseased, the presence of pests and so much more without actually going to see the plant. Turning these images into assets, this company brings the real world into the digital one to help you better grow food.

    Intelligent Growth Solutions

    A vertical farm technology company founded by an actual farmer (fairly rare, believe it or not!), this startup has its own patented solutions of vertically-stacked growing systems to create ideal conditions to grow your plants. In a country with highly competitive uses for land, innovations in this space would allow us to maximise food production using far less space than conventional land-based agriculture.

    uFraction8

    As the cultivated meat market gains traction, key challenges around scaling remain, mostly tied to production capacity. The industry needs more efficient, resilient solutions in order to both lower costs of production and achieve economies of scale. This start-up is innovating new ways to build what it describes as the most efficient and scalable filtration solutions that have ever existed to solve the problems with harvesting and processing microbial cell cultures. The company’s enabling technology could remove major barriers as their product could be an important enabling technology that could make meat from cellular agriculture more accessible.

    Bright Biotech

    Bright Biotech is part of the relatively new sector of molecular farming, a type of food production technology that makes use of plants as production houses. The company uses chloroplasts to obtain large amounts of high-value proteins from plants using light, which results in scalable and low-cost proteins that can help cultivated meat players overcome their protein supply challenges.

    Higher Steaks

    Last but not least, is Higher Steaks, the startup with the punniest name by far. The company specialises in cultivated fatty meat and unveiled the world’s first cultivated pork belly and bacon without the use of genetic engineering last year. In fact, the company shared that they are working on “dong po rou” (braised pork belly) specifically for the Asian market. It’ll be interesting to see how they replicate the texture and melty characteristics of such a dish. High stakes indeed.

    Mounting challenges means a host of opportunities for innovative startups to truly revolutionise the way we produce and consume food. It was empowering to witness the passion of the founders of these companies as they take on the opportunity of a lifetime: securing a stable, nutritious, and climate-friendly future of food.

    The post These 8 UK Agri-Tech Startups Want To Future Proof South East Asia’s Food System first appeared on Green Queen.

    The post These 8 UK Agri-Tech Startups Want To Future Proof South East Asia’s Food System appeared first on Green Queen.

    This post was originally published on Green Queen.

  • cowabunga milk

    9 Mins Read

    By: Beatriz Franco, Managing Partner at Vita Vera Ventures, and Maya Benami, PhD, Advisor to Vita Vera Ventures & Technical/R&D Consultant.

    Climate tech investors are missing out on a food technology solution with major GHG emissions-lowering potential, argue food tech experts Beatriz Franco and Maya Benami.

    Current food production is not only a driver of climate change, but it is also a victim of climate change.

    This means that, unfortunately, we cannot expect our food supply to continue at current levels. Combined with the added pressure of population growth, it is clear we will need to integrate emerging food technologies into our food supply system in order to support the demands of humanity, as well as the latter’s sustainability and resiliency.

    Climate tech investing has significantly increased in the last few years, based both on the urgency for solutions as well as the clear business opportunities it offers. However, we continue to see that investors are not appropriately targeting technologies with the highest potential for reduction of greenhouse gas (GHG) emissions, and in the process, overlooking opportunities for both impact and returns.

    PWC’s State of Climate Tech report notes that the food and agriculture sectors are tied to nearly a quarter of all global GHG emissions (some say up to 1/3 of emissions) but they received only 12% of global climate tech venture funding. Meanwhile, the mobility sector received almost 50% of global climate tech venture funding in 2022, yet is responsible for only 15% of global GHG emissions.

    This is why we are shining a light on one fast-growing food technology sector that is still largely misunderstood, despite its immense potential: precision fermentation.

    What is Precision Fermentation?

    Fermentation itself is not new. Humans have been consuming fermented foods, such as cheese and alcohol, for centuries. They are made through traditional fermentation methods, where microorganisms, such as yeasts, transform sugars into an ingredient, new food, or beverage in order to remove toxins, increase shelf life, and/or improve taste and digestibility.

    Precision fermentation is a more advanced form of fermentation. It turns microorganisms, like yeast and bacteria into ‘factories’ to produce specific end-products such as proteins, enzymes, fats, vitamins, flavors, or pigments. Those microorganisms are fed carbon-based compounds, such as sugars, and are engineered and optimized to produce replicas of an organic molecule, such as protein. Precision fermentation is already used in pharma for the production of compounds such as vaccines and insulin, and it is now being applied to food production as well.

    In the past, insulin was harvested from cattle and pig organs. This process was highly inefficient at best, requiring tons of pig parts in order to obtain just a few ounces of purified insulin, not to mention that this non-human insulin ofte caused allergic reactions in many patients. Today, insulin is produced through precision fermentation by inserting the human insulin gene into a microbe and prompting it to produce human insulin.

    As far as new food applications go, examples of exciting products in development or in production through precision fermentation include whey protein, casein to make cheese, palm oil alternatives, animal fat, collagen, and even breast milk proteins for infant formulas.

    Seizing the Opportunity, Why the Disconnect?

    With so many opportunities for impact and returns, why aren’t we seeing more generalist investors looking into food tech?

    We believe one big challenge comes from the fact that it is becoming more complex to assess the opportunity given the evolution of new processing tech and biotech methods. Also, given its nascency, many companies are still in R&D and lab-scale phases, thus too early in their journey to offer revenue and customer metrics to analyze traction during investor diligence.

    Can investors leverage the biomedical sector as a proxy during diligence?

    Unfortunately, it’s not that simple. While some scientific aspects of pharmaceutical and biomedical diligence can offer comparative insight, other aspects can be quite different, especially when considering that the goal of food production is to make much larger quantities at much lower price points. Accordingly, business strategy as well as processing and equipment requirements can differ significantly.

    Drugs created via precision fermentation for the pharmaceutical industry are grown in expensive highly controlled bioreactors that are suitable for the production of high-value, low-volume products.

    The food industry, on the other hand, needs to create affordable, high-volume food compounds produced in food-grade conditions. This is why we are seeing so many new startups focused on building the infrastructure and enabling technologies around alternative foods, including built-for-purpose fermenters and bioreactors.

    One other difference to highlight is on the regulatory side. The regulatory process for novel foods can be perceived as easier and faster when the primary goal is to demonstrate that the new food is substantially equivalent to an existing food. Biopharma, on the other hand, needs to go through the rigorous testing required for new medicines that are often administered to immune-compromised patients.

    It is interesting to note that there are differences in the way scientists in these two industries approach their products. A cell biologist that works in the pharmaceutical industry will not be concerned (or necessarily understand) the nuances of what is needed to make a successful food product, which includes specific consideration of each sensory property, such as flavor, texture, and color, and using only food-grade reagents.

    Starting from the ground up?

    You might be thinking: is this new (old) tech a black box? Well, yes and no. Precision fermentation relies on living organisms and cells as part of its process. While biology is the oldest ‘technology’ in the world, so much is still not well understood, such as the mechanisms of cell communication and the complexities of cell organization.

    That being said, humans have been successfully using biology for advancement long before understanding the science behind it. See: the birth of agriculture- we’ve grown crops and bred livestock for over 12,000 years.

    These days, genetic screening, cell manipulation technologies, artificial intelligence, and machine learning greatly enhance our understanding of cell processes by pinpointing genetic sequences that are responsible for protein production pathways in a cell, just to take one example. So now scientists can use what we do know and build upon it to harness natural processes.

    Using precision fermentation, we can leverage microorganisms to sustainably create a vast array of known and novel foods and ingredients, from meat, dairy, seafood, eggs and honey to specific flavors such as new sweeteners, taste enhancers, and much more.

    The investors’ journey: important aspects to unpack during diligence

    So what should an investor look for during diligence? While there are many angles to be evaluated such as market opportunity, team, competitive landscape, IP, and moat, among others, commercial traction is most likely not going to be available at this stage.

    In order to address the intricacies of this nascent industry and its specific requirements, we unpack the key points that investors should take into consideration when performing diligence on a precision fermentation company.

    Customer Validation

    While it’s true that early-stage companies will have little to show in terms of revenues and customer traction, the next best thing to review is customer validation. Investors can and should talk to potential customers and validate that the product is actually solving a real need.

    Some companies will have LOIs, initial partnerships and customer trials; they may even have surveys that can provide an indication of what a potential customer is thinking. That being said, a phone call with a potential customer in your network is still advisable, not only to understand how important that solution really is but also to evaluate their willingness to pay for such a solution.

    Proof of Concept and Scalability Mindset

    As mentioned, many companies in the precision fermentation space are currently at lab-scale/ R&D phase. In the very earliest stages (lab-scale, where most companies are), they will be creating prototypes and proofs-of-concept and producing a few grams to a few kilograms per batch and using fermenters under 20L and likely between 1L and 5L.

    As they progress and move to pilot, demo, and commercial scale, quantities produced, and size of fermenters increase accordingly but one important thing that some investors forget, is that not all products are created equal. If a precision fermentation company is targeting products that represent a small percentage of the final food formulation, such a company will be able to go to market with a higher price point than one whose product makes up the bulk of the final food formulation, and therefore their path to a viable commercial scale is shorter. Investors should be aware that a viable commercial scale can vary in size significantly depending on the target product.

    In all cases, investors should always look for founders with a “scalability mindset”. In other words, no matter how early a company is in its journey, founders should be thinking about scalability from the start. This is shown through each of their decisions during technology & process development. For example: Are they frontloading their cost analysis while building their process? Did decisions around inputs take into consideration availability and supply chain resiliency? Are they already planning for their equipment needs and establishing partnerships?

    Scaling is one of the trickiest parts of the success of this industry. In addition to scaling up the technology itself and accurately forecasting budgeting needs, companies face an additional challenge: the bottleneck of little-to-no-fermenter availability, both from a co-manufacturing standpoint or direct purchase. Many fermenters available today are currently prioritized to produce high-value, lower volume pharmaceutical grade vaccines and drug compounds. Companies are purchasing biomedical infrastructure or fermenters from biofuel facilities or other industries and attempting to repurpose them, which is far from ideal.

    However, we expect and hope to see a positive change in this space in the near future given not only the surge of new companies tackling this problem but also the increasing interest shown by governments around the world through regulation and potential investments targeting the development of the industry.

    Process Feasibility, Efficiency & Optimization

    This is an important part of diligence: investors need to dig in and understand where the company’s process is at and how efficient both the upstream and downstream processes are. A critical aspect here is to ascertain how much final product you get at the end of the process and how long that takes from start to finish. This involves getting at how much product the microorganism secretes, how fast, and how much product is recovered after purification.

    Investors should not only be clear about where a company is today, but also where it’s going tomorrow and when it will be profitable, which is why reviewing its optimization plans and efficiency targets is vital, much like they would financial projections. All assumptions embedded in these plans should be checked to ensure they are realistic and reasonable.

    It’s Time to Seize the Opportunity

    Not a day goes by without media headlines reminding us of the consequences of the climate crisis. Now is the time to focus on technologies that can solve for these, particularly as they affect our global food system, and investors should be prioritizing solutions that can reduce the most GHG emissions.

    We have no doubt that precision fermentation will, together with other emerging food technologies, be a much-needed part of the answer to building a more resilient food system.

    And here is the proverbial cherry on top: there is real money to be made by investors. Climate tech is not only our biggest hope in the fight against climate change, but it is also simply good business. As it stands, the global food market represents a not insignificant 10% of the world’s GDP, and with a growing population to feed, demand will only increase.

    Startups that can offer good substitutes for foods whose current emissions costs is too high for our future world to bear (i.e. meat, dairy, eggs) at the right price and with a lower carbon footprint will undoubtedly find success- and those companies who can do so at a higher quality and a lower price will knock it out of the park. It’s time to invest in the future of food.

    Beatriz Franco is a Managing Partner at Vita Vera Ventures, a Climate Tech fund investing in vital innovations advancing the resiliency, efficiency and sustainability of the food industry.

    Maya Benami, PhD is an author and R&D consultant specializing in cellular agriculture, fermentation, microbiology, plant biochemistry, and environmental sustainability. She advises venture capitalists, start-ups, and global food and beverage firms on R&D, due diligence, and product development.

    An earlier version of this article was previously published on Medium.

    The post Overlooked and Underfunded: Are Climate Tech Investors Missing Out On Precision Fermentation? appeared first on Green Queen.

  • 6 Mins Read

    Green Queen‘s Sonalie Figueiras shares her reservations about Vow’s global headline-grabbing cultivated mammoth meatball event with company founder and CEO George Peppou in this exclusive interview.

    “We created the mammoth meatball to serve as a starting point for this conversation.” So writes George Peppou, the founder and CEO of Australian cultivated meat company Vow, in a Medium post about the startup’s unveiling of a cultivated meatball made with DNA cells from the extinct wooly mammoth.

    It’s safe to say that the company achieved this goal and more. In fact, chapeau to the entire Vow comms team, who did a phenomenal job and deserve a raise! (Or at least a bonus!). The mammoth meatball unveiling is likely the most talked-about cultivated meat event ever. As someone who covers the alt protein space closely, I can safely say I have never seen more earned media for such an industry announcement. Not only was the news broken by The Guardian, the story was also picked up by almost every major global news outlet: Bloomberg, TechCrunch, Business Insider, ABC, the Washington Post, the BBC to The Times all covered it. It made US television, with a bit on The Late Show with Stephen Colbert, which attracts an audience of over 2.3 million viewers. Even that altar of prestige journalism, The Atlantic, weighed in. We at Green Queen published the story too, nach.

    While the vast majority of the coverage has been positive, a select few have questioned. Gizmodo‘s Isaac Schulz wrote about his take in a piece titled: I Hate The Mammoth Meatball. Truth be told, I share many of Schulz’s reservations.

    Last year, a London-based startup called sent us a press release about their mission to produce cultivated lion and tiger meat and we chose not to cover the story. It seemed gratuitous, arrogant and entirely beside the point of the alternative protein industry’s raison d’être. The mission of this sector is to solve for food security and usher in an era of global food production that is safe, ethical, sustainable and nutritious. Why on earth would we want to do anything to glorify the consumption (and killing) of majestic, endangered creatures like lions and tigers? God forbid that this type of stunt would justify and embolden the already too numerous trophy hunters of today.

    Still, Vow is a well-established, mission-driven cultivated meat player who last year raised the largest Series A in the sector ever. Peppou, who is seen by many as a true and fearless visionary when it comes to the future of food, has spoken many times about the company’s goal to “invent entirely new meats” and has hinted at a future of cultivated zebra and kangaroo meat. I wanted to get more context from him about how the team decided to go ahead with the meatball and he kindly obliged – our interview below.

    A mashup of the Vow mammoth meatball media coverage – Courtesy Vow Product Manager Sarah Ellis’ Linkedin post.

    Sonalie Figueiras: You have said you did this to bring cultivated meat into mainstream conversation. Is this the right conversation? It could be argued that promoting extinct species consumption does not address climate change or food security, or health, ie the main motivators to disrupt food with cultivated meat? 

    George Peppou: Two key points here: (1) We needed to do something so outrageous that it would break through into mainstream media. The original cultured meat hamburger was produced 10 years ago, and yet the mainstream media still rarely covers any large advancement in cultured meat. The mammoth meatball project has been covered extensively, and has a whole new cohort of people talking about whether or not they would eat cultured meat. (2) While the mammoth meatball is a product concept (and not something we currently plan to bring to market), it is still produced using cultured meat technology, so all of the sustainability benefits that apply to cultured chicken, still apply to cultured mammoth. 

    Stephen Colbert showcases Vow’s mammoth meatball – via Twitter.

    Sonalie Figueiras: Do you worry that this could risk weaponizing the narrative of cultivated meat in the vein of the dangers of ‘bringing Jurassic Park to life’ narrative? 

    George Peppou: No. We are not bringing whole animals to life. That is definitely a criticism aimed at others but isn’t relevant here. For every one person who says “ew” there seems to be another two saying “yes, please!”.

    Sonalie Figueiras: On the conservation front, Gizmodo journalist Isaac Schultz writes: “When you think of the woolly mammoth, do you think “the future of food?” I don’t. What’s next—polar bear patties? Sea turtle stew? I don’t think a product designed to be salivated over and consumed is the best way to bring attention to climate change and conservation issues, even if the meat is lab-cultivated.” How would you reply to that?

    George Peppou: I think the very fact that Isaac has written an article about cultured meat, the future of food and sustainability indicates that this project has had its desired effect. We are having conversations today that we simply weren’t having yesterday. Cultured meat is (hopefully) only a few months away from being sold in the US, and yet still, very few consumers are familiar with what it is. 

    Courtesy George Peppou

    Sonalie Figueiras: Do you worry it may put off regulators, particularly in geographies where they are already skeptical of the technology, and that they may see this as a distraction / gimmicky?

    George Peppou: No, every regulator and country we have worked with has been incredible. The reactions from regulators have been the same as the public, entertained by the spectacle and aware that mammoth is a stunt, not a product. There is real support from within the regulatory bodies we have spoken to, to ensure that cultured meat can be brought to market in a safe manner. If it is not safe, it is not food. 

    Sonalie Figueiras: Do you wonder about the political ramifications of such a tasting, with the pro-meat lobby weaponizing the news to further push their anti-innovation, anti-food-tech agenda by saying that if funds were to be allocated to the space, they would be used for non-essential purposes rather than to sustainably feed the world? 

    George Peppou: To be clear, there was no tasting of the mammoth meatball. This was a concept used to start a discussion and bring cultured meat into the mainstream discussion. Throughout the press around the meatball project we have been very clear about our belief that traditional agriculture and cultured meat will need to co-exist. Cultured meat is not going to replace traditional agriculture in the near future, but it does provide an important source of high-quality protein in a sustainable manner.  

    Sonalie Figueiras: Lastly, and this was my biggest concern personally with the other startup that says it’s working on cultivated lion and tiger, do you worry that this kind of event will serve to glorify the consumption of endangered animals? 
    George Peppou: This is a valid question and something that we have spent a lot of time thinking and talking about internally. In the case of this particular project, we don’t believe that this is a concern (as the mammoth is already extinct).

    The post Vow Founder On That Mammoth Meatball: “We Needed To Do Something So Outrageous That It Would Break Through Into Mainstream Media. appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 4 Mins Read

    “You can literally smell the pig and cow sh*t all around you”: A food technologist and Italian transplant living in one of Italy’s main pork production regions shares her feelings about the government’s push to ban cultivated meat.

    Yesterday, the Italian government endorsed legislation that would prohibit the production of laboratory-made meat, feed and other “synthetic” foods. The country’s agriculture minister emphasized that the bill was aimed at protecting Italy’s agri-food heritage and health protection. In recent months, agricultural organizations including Coldiretti, Italy’s biggest farmers’ association, have amassed half a million signatures demanding protection for “natural” food against “synthetic” food. Prime Minister Giorgia Meloni, part of the right-wing Brothers of Italy political party, is among those who have signed it.

    If the bill passes, Italian food producers will be prevented from producing food or feed from animal cell cultures or tissues; violators would face up to €60,000 in penalties.

    Here’s what they’re not telling you about Italy’s so-called “protection of food culture and tradition” in relation to heavy fines for cultured meat: You can literally smell the pig and cow sh*t all around you in the main regions of Italy that specialize in producing the country’s traditional meat and animal-based products. One of those regions is Emilia-Romagna, where I live with my family. 

    I’ve been living in the aptly-named “Italian food valley” for the last few years, the land of world-famous foods like prosciutto di Parma and Parmigiano Reggiano. The food here is incredible. Even fruits and vegetables are some of the best on the planet.  Living here, I re-learned an important lesson: food is best enjoyed outside the “fast-food” culture.

    Imagine yourself inside a car driving by fields and factories where animals are reared. You see all these beautiful sights: lush vineyards and bright green fields. But oh, the smell!  The car’s windows are closed but you can still smell the stink from the animals. The cows and pigs in their pens. The odor permeates everywhere; it’s inescapable. The air quality is bad. So, so bad! This is a reality of life for people like me who live in these areas.

    And it’s the price we pay for all those delicious meat- and dairy products the region produces. It makes sense that people want to protect it- it’s a very successful industry. Meat accounts for a whopping 57.7% of total exports from the region. The whole world craves our Parma ham. 

    You love your polpette, ragú, gnocco fritto and all the many types of salumi? Fill your lungs with this air. It has become so normal it is a part of the food culture and heritage.

    And the stench is only one (awful) part of it. There are also all the resources that producing meat the “natural” and “traditional” way requires. The water. The feed. The workers. Remember the drought last year? This year doesn’t seem to be any better after a winter of little rain and snowfall.

    If this rebranding by Italy’s Ministero delle Politiche Agricole, Alimentari e Forestali (MiPAAF) is about food sovereignty, then this move counters that.

    Because people should have freedom. And that means choices. Choices around the foods we eat and how they are produced. But also, the freedom to choose a future where people’s health, food tradition, and the planet’s future are not compromised.

    I feel so conflicted about all of this, particularly because Italy is where I first came across the idea of cellular agriculture. I moved here to get my master’s in food innovation and Dr. Mark Post (the Dutch scientist who first created cultivated meat and the founder of OG cultivated meat company Mosa Meat)  was our visiting professor. We attended his lectures and worked on related experiments in a lab right here in Italy. A few months later, my team was researching solutions for the future of meat, and cultivated meat emerged as one of our biggest findings. 

    I’ve had many a discussion with my Italian partner during which I’ve shared how much the sight of a basic steel tank and the centuries-old fermentation tradition it represents excites me. Italians have mastered the microscopic world and I can easily picture Italy as a leader in cultivated and fermentation-based protein technologies, after all, Italians are masters of flavour, fermentation and great stewards of culinary tradition, traditions, that were born out of innovation many centuries ago.

    If the country’s meat and dairy industry feels threatened, this new regulatory move doesn’t sound like a bold move. It feels desperate. And if history is our teacher, we know that we don’t achieve greatness when we operate from fear.

    When I talk to my Singaporean friends, they have a totally different mental model. The Lion City state’s government has understood what’s at stake: nothing short of their national food security. Singapore’s 30 by 2030 plan, which involves ensuring that the country achieves 30% domestic food production by the year 2030, has enabled the city-state to become Asia’s food tech capital. In 2020, it became the first country to approve the sale of cultivated meat, a bold move that made headlines around the globe. China has recently pledged its support to alternative proteins too. These countries see the (climate crisis) writing on the wall. 

    Italy has all the elements in place to be a future food leader: knowledge (both modern and traditional), resources, and one of the best climates for growing food on the planet (if you have ever tasted a fresh, ripe Italian tomato, then you know.

    My hope for Italy? That tradition and technology can co-exist so my Filipina-Italian daughter gets a chance at a safe, ethical and sustainable future. 

    An early version of this article was first published on social media.

    Disclaimer: Jennibeth does work for Green Queen. This had no effect on the publishing of this editorial.

    The post OpEd: What The Anti-Cultivated Meat Brigade Aren’t Telling You About Italian Pork & Beef Production appeared first on Green Queen.

    This post was originally published on Green Queen.

  • TissenBioFarm shows off its cultivated meat
    4 Mins Read

    TissenBioFarm debuted a giant piece of cultivated meat at the opening of South Korea’s Cellular Agriculture Support Center in the North Gyeongsang Province.

    This story has been updated at 13.00 on 31 March 2023 with additional information about the company’s 10kg cultivated meat prototype.

    South Korea’s North Gyeongsang Province has announced the opening of the North Gyeongsang Cellular Agriculture Industry Support Center. This 2,309㎡ facility was built over six years with a total investment of KRW 9 billion (approx. USD$7 million), and it aims to develop biomaterials and support companies in the cultivated meat sector.

    South Korean startup TiessenBio Farm, which raised more than $1.6 million in a Pre-Series A funding round last September, unveiled a 10-kilogram piece of cultivated meat on the occasion.

    The North Gyeongsang Cellular Agriculture Industry Support Center

    The four-story building houses laboratories, analysis rooms, and quality control rooms. The second floor will host five companies and Yeungnam University Cell Culture Research Center, while the third floor will feature research and analysis rooms with 55 types of corporate equipment to be installed by 2024 with a budget of KRW 3 billion.

    The North Gyeongsang Cellular Agriculture Industry Support Center opening ceremony launch. | Courtesy

    “The Cellular Agriculture Industry Support Center opened in Uiseong, where a new airport will be built, is expected to play a pivotal role in advancing a high-tech industry,” Cheol-Woo Lee, Governor of North Gyeongsang Province, said at the launch. “We will continue our support and investment in promising new industries.”

    The opening ceremony was attended by about 200 people, including government officials, university representatives, research institutes, and private companies. The site tour showcased five companies, including TissenBioFarm, which unveiled a 10kg cultured meat prototype to the public for the first time. The company claims it is the world’s largest piece of cultivated meat to date.

    Green Queen contacted the company for further information to clarify the percentage of cultivated cells and tissue, scaffolds used and what other ingredients the piece contains. We also asked the company to specify what type of animal meat this is. So far, the company has not replied.

    Update: Tiessen’s Chief Strategy Officer La Yeonjoo told Green Queen the following via email: “This prototype is a hybrid cultivated meat, consisting of cells and bioink. We have developed original technologies that can make cultured meat of this size while keeping nearly all the cells alive.”

    The prototype’s ingredients are as follows: animal cells, bioink, food coloring, palm oil and food adhesive.

    La says the company has not yet publicly disclosed the % of cells of this prototype publicly because “it doesn’t appropriately represent the company’s capabilities”, adding that the event organizers at Cellular Agriculture Support Center asked them to make a prototype on very short notice. TiessenBio made it in their small lab in just a few weeks and La said they didn’t have enough time to grow the cells “as much as we wanted to and could have.”

    “By the end of this year, we will scale up our cell culture infrastructure, and will showcase 100% cultivated meat (that would translate into approx. 80% cells + 20% bioink and other biomaterials),” she added.

    North Gyeongsang Province has also announced its Cellular Agriculture Industry Promotion Strategy, which plans to link with the vaccine, drug, cosmetics, and green bio industries. Uiseong-gun is creating the Uiseong Bio Valley General Industrial Complex for the integration of the cellular agriculture industry.

    South Korea’s cultivated meat sector

    The opening of the North Gyeongsang Cellular Agriculture Industry Support Center marks a milestone in South Korea’s efforts to develop the cellular agriculture industry. With this center, the country hopes to become a leader in this emerging field.

    The center launch comes after 28 key industry stakeholders in South Korea signed a memo of understanding in February to advance the country’s cultivated meat industry.

    TissenBioFarm's giant piece of cultivated meat
    TissenBioFarm’s giant piece of cultivated meat | Courtesy

    The North Gyeongsang Province led the MOU. Other signatories include city governments (Pohang-si, Gyeongsan-si, Gumi-si, Uiseong-gun), universities (POSTECH, Yeungnam University), research and technology institutions (Korea Food Research Institute, Gyeongbuk Technopark, Pohang Technopark), and corporations including cultivated meat startup TissenBioFarm, health food manufacturer Ildong Foodis, and functional food ingredients developer Neo-Cremar. 

    “We are working on groundbreaking technologies to overcome key challenges in the cultivated meat field,” TissenBioFarm CEO Wonil Han said in a statement at the time. “Once it is done, South Korea will be a global game changer in the field.”

    The post South Korea’s Cellular Agriculture Support Center Opens With a Bang: The World’s Largest Piece of Cultivated Meat appeared first on Green Queen.

    This post was originally published on Green Queen.

  • Magic Valley pork wontons

    5 Mins Read

    Cultivated pork meat is Magic Valley’s latest achievement, following the launch of its lamb meat last year.

    Melbourne-based Magic Valley says its cultivated pork meat comes from skin cells retrieved humanely from a living pig. The cells are then grown using the company’s breakthrough technology that replaces fetal bovine serum.

    ‘An ethical and sustainable solution’

    According to Magic Valley, its tech allows the cells to replicate infinitely, turning into both muscle and fat — all from a singular skin scraping. The startup says this makes it a more stable and faster tech than those achieved by other cultivated meat producers. It says its tech is scalable for all types of meat, not just pork and lamb.

    “The global need for alternative proteins to meet the demands of the growing population is imperative as we take that journey to achieve net-zero, steering clear of traditional ways of consuming meat for ethical and environmental reasons,” Magic Valley founder and CEO Paul Bevan said in a statement.

    Unlike other players, Magic Valley does not rely on fetal bovine serum (FBS) as a growth media for its products. “We don’t need a replacement for Fetal Bovine Serum (FBS) in our process, as we have never used it! Instead, we have developed our own proprietary growth media that is completely animal-origin-free, setting us apart from many of our competitors,” Bevan told Green Queen over email.

    “By eliminating the need for FBS, we are able to align our production process more closely with our core mission of promoting a more sustainable and ethical food system, and maintaining a strong commitment to sustainability and animal welfare,” he added.

    Pork format, cost per kg and cultivated material percentage

    The company is starting with pork meat in a minced/ground format to address “the growing concerns about the ethical and humane treatment of pigs in traditional meat production”. Pork is a widely popular protein source enjoyed by millions of people globally. In many parts of Asia, including China, it is the most consumed animal meat per capita.

    Bevan told us that its initial minced pork products are designed to contain approximately 20% cultivated material. “This percentage has been carefully selected as it allows us to effectively replicate the taste, flavour, and aroma characteristics of a traditional minced meat product, ensuring a satisfying eating experience for consumers.”

    He says that by incorporating 20% cultivated material in their product, they can “balance the benefits of our innovative cell-cultured technology with the practical aspects of production and consumer preferences.”

    Currently, production costs for Magic Valley’s minced pork product stand at $33/kg. Bevan recognizes this may seem high compared to conventional pork prices but is careful to underline that the company is in its very earliest stages and has significant potential for improvement. He says he is targeting a cost of $3.30/kg in the future to ensure competitiveness in the market.

    “As we move forward with our plans to establish a pilot plant facility and scale up production, we anticipate benefiting from economies of scale.”

    Actively fundraising and working with Australian regulators

    The news amidst active fundraising efforts for the company. Bevan told us that the company is aiming to raise $3 million to “support the next phase of growth and development”. The goal is to use the funding to work on regulatory approval for Magic Valley’s lamb and pork products, scale up production capacity and develop its first pilot plant facility.

    Bevan told us that he and his team are “actively engaged” with Australian regulators, particularly Food Standards Australia New Zealand (FSANZ), which he says is known for its proactive approach towards novel food technologies. The agency recognizes “the potential benefits it can bring in terms of sustainability, animal welfare, and food security” and has established a clear and comprehensive framework for companies like Magic Valley to follow.

    He described the process as “consultative” in nature and the communication flow as very “open and transparent”, with a great deal of collaboration with the regulators, with regulator meetings and discussion around Magic Valley’s technology and processes in order to address any concerns or questions raised.

    Magic Valley founder Paul Bevan
    Magic Valley founder Paul Bevan | Courtesy

    The global cultivated meat market is set to reach $630 billion by 2040 — representing what Bevan says is an enormous opportunity for Australia to benefit from and contribute to the industry that is aligned with the UN’s Sustainable Development Goals.

    “So, with both the need and desire for new forms of protein, and the global economic opportunity growing exponentially, our newest cultivated pork milestone puts Magic Valley in good stead to capture a sizable market share to feed future generations,” Bevan said. He says the company’s cultivated pork products provide the exact same flavor experience for consumers that enjoy conventional pork. “It is an ethical and sustainable solution and at scale, our products will be much cheaper than traditional alternatives,” he said.

    Next up, the company will dive into cultivated beef, angling toward a full range of meat options as regulatory approval is expected in 2024.

    Food tech in Australia

    The news follows a string of announcements out of Australia this month. Earlier this week the precision fermentation company Cauldron announced a AU$10.5 million raise to build Asia-Pacific’s largest network of precision fermentation facilities. And in the cultivated meat category, Vow says it has created a meatball using cells from the extinct wooly mammoth as part of a project to showcase the potential of cellular agriculture. 

    Vow Cultivated Meat Factory
    Vow’s Factory 1 was announced last year | Courtesy

    Bianca Lê, Honorary Fellow at The University of Melbourne; Technical Strategy and Growth Manager at Mission Barns; and Board Director, Cellular Agriculture Australia, recently called for Australia to develop standards for biotechnology, including cultivated meat, as the nation is particularly vulnerable to climate change and needs food solutions.

    “Australia has been one of the world’s top three beef exporters for more than 70 years. We’re also a biotech leader. Two decades ago, Australia’s biotech sector was tiny. Now it’s amongst the top five in the world,” she wrote.

    “As we face an increasingly uncertain future, it might be a smart move to secure our food supply while protecting ourselves against climate change – and reducing environmental damage.”

    The post Australia’s Magic Valley Debuts Cultivated Pork Meat appeared first on Green Queen.

  • 4 Mins Read

    Cultivated meat innovation company CULT Food Science has acquired consumer brand assets, two patents, non-scientific IP and product formulations from cultivated pet food startup Because Animals.

    CULT Food Science, a publicly traded Vancouver, Canada-based cultivated meat innovation company, announced yesterday in a press release titled posted to its website that it had signed a binding Letter of Intent (LOI) to acquire the consumer brand assets, related patents, non-scientific intellectual property, and product formulations (referred to in the release as “the Assets”).

    The Assets include a yeast-based dog treat (noochies), a yeast-based dog food and two provisional patents for rehydrated-then-freeze-dried-yeast-probiotic-based pet supplements.

    According to the release, these assets will be combined with CULT’s existing pet food brands to form a new Pet Food Division that will work to develop and commercialize cultivated pet food products.

    Confusion around LOI news media coverage

    There was some initial confusion yesterday surrounding the LOI news, with social media posts and smaller media outlets suggesting that Because Animals had been entirely acquired and one platform that contacted us describing it as the “World’s First Cultured Meat Brand Acquisition”.

    In a statement sent to Green Queen via email regarding the original CULT press release, Shannon Falconer, co-founder and CEO of Because Animals reiterated that “Although it’s not clear from the press release, the consumer brand ‘Because Animals’ was not acquired.”

    Instead, Falconer told us that the company is focusing all its resources to accelerate the commercialization of its cultured meat technology. As a result, it discontinued the sale of its nutritional yeast-based products late last year and had recently agreed to sell all formulations and two provisional patents related to these discontinued products to Joshua Errett.

    Falconer added that “Because Animals retains all of its intellectual property relating to cultured meat – which is our core business – and we are committed to revolutionizing the pet food industry with this technology.”

    When asked to confirm the news mentioned in the release, Lejjy Gafour, CEO of CULT Food Sciences, told us via email that “as stated in the release formally on our website”, the news announcement referred only to the acquisition of “Because Animals Inc.’s consumer brand assets, related patents, non-scientific intellectual property, and product formulations” and directed us to “additional clarifying language included in the release which the other outlets or individuals may have overlooked”, which says that “Because Animals Inc will continue to innovate in the pet food industry.”

    Former Because Animals co-founder joins forces with CULT

    Errett is the former COO and co-founder of Because Animals. He departed in September 2022 according to Linkedin profile and on October 31, CULT announced that Errett had joined the company as Vice President.

    “The CULT platform is one of the most ambitious and comprehensive in the field of cellular agriculture. It has endless potential to impact the world’s food supply and so I’m thrilled to be a part of it,” added Mr. Errett.  

    Earlier this month, CULT, which according to its website is focused on “providing investors with unprecedented exposure to the most innovative start-up, private or early-stage cultivated meat, cell-based dairy, and other cultured food companies around the world”, revealed that Canadian biotech and cannabis entrepreneur Marc Lustig had acquired a 15% stake in the company, making him the largest single shareholder

    “I am very excited to have taken a significant ownership stake in CULT Food Science. I believe it is inevitable that cell-based foods will sustainably transform our food systems for the better, and that these products will be coming to market much sooner than most people think. As a first-mover in the cellular agriculture space, CULT has the opportunity to play a unique and valuable role in the industry’s exciting scientific innovation,” said Lustig of the investment news.

    Pet food is a growing focus area for cultivated meat startups

    Because Animals was founded in 2016 by Falconer and Errett, and backed by leading VC funds including Draper Associates and SOSV. It was one of the first companies globally to focus on developing pet food aimed at dogs and cats using cellular agriculture technology and in August 2021, debuted the world’s first commercially available cultivated cat food. In early 2022, Because Animals secured investment from European CPG company Group Orkla SA, bringing the company’s total funding to $6.7 million.

    Colorado-based Bond Pet Food created cultured chicken aimed at pets in 2020 and last November, vegan dog food company Wild Earth, which famously got Shark Tank judge Mark Cuban to invest $550,000 in 2019, said it had developed a cultivated chicken broth topper “aimed at making the category more sustainable”.

    The post Because Animals Sells Off Discontinued Products To CULT Food Science To Accelerate Cultivated Pet Food Technology appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 4 Mins Read

    Australian cultivated meat company, Vow, has created a meatball using cells from the extinct wooly mammoth as part of a project to showcase the potential of cellular agriculture.

    Vow’s mammoth meatball is a token product showing not just how cells from unconventional species can create new kinds of meat, but also as a symbol of both biodiversity loss and climate change.

    Mammoths went extinct in large part due to human hunting as well as post-ice-age planetary warming. The novel meatball was unveiled on Tuesday at the Nemo science museum in the Netherlands.

    “We have a behaviour change problem when it comes to meat consumption,” Vow CEO George Peppou said in a statement.

    “The goal is to transition a few billion meat eaters away from eating [conventional] animal protein to eating things that can be produced in electrified systems.

    “And we believe the best way to do that is to invent meat. We look for cells that are easy to grow, really tasty and nutritious, and then mix and match those cells to create really tasty meat.”

    A copy of the invitation for Vow’s Wooly Mammoth Meatball tasting

    Cultivating curiosity

    While most cultivated meat producers are tackling conventional meat such as chicken, pork, beef, and fish, Vow is taking a different approach by investigating the potential of more than 50 less common species, including alpaca, buffalo, crocodile, kangaroo, peacocks, and various types of fish. Tapping into human curiosity to taste less conventional meat could help acclimate consumers toward the novel cell tech, the company says.

    Vow Cultivated Meat Factory
    Vow’s Factory 1 was announced last year | Courtesy

    The mammoth muscle protein was created by Vow along with Professor Ernst Wolvetang at the Australian Institute for Bioengineering at the University of Queensland. The team used DNA from mammoth myoglobin, a key muscle protein that gives meat its flavor, and filled in a few gaps using elephant DNA. This sequence was placed in myoblast stem cells from a sheep, which replicated to grow to the 20 billion cells subsequently used by the company to grow the mammoth meat.

    “It was ridiculously easy and fast,” said Wolvetang. “We did this in a couple of weeks.”

    Mammoth was the second choice. The initial idea came from Bas Korsten at the creative agency Wunderman Thompson. The team wanted to replicate dodo bird meat, but there is no DNA available for replicating.

    Mammoth worked just as well symbolically though. “Our aim is to start a conversation about how we eat, and what the future alternatives can look and taste like. Cultured meat is meat, but not as we know it,” Korsten said.

    Vow is not the first food tech company to explore mammoth protein. Last year the startup Paleo explored creating woolly mammoth “paleo protein” via its novel precision fermentation heme technology. And the biotech company Colossal is using CRISPR technology to potentially resurrent the species, which it says could play a crucial role in protecting ecosystems that trap and store carbon.

    Cultivating sustainable protein

    Like other cultivated meat offerings, Vow says cultivated meat uses much less land and water than livestock and produces no methane emissions. The energy Vow uses is all from renewable sources, and the company does not use the controversial growth medium, fetal bovine serum.

    No one has tasted the mammoth meat yet, though. “We haven’t seen this protein for thousands of years,” said Wolvetang. “So we have no idea how our immune system would react when we eat it. But if we did it again, we could certainly do it in a way that would make it more palatable to regulatory bodies.”

    Vow quail meat, Morsel | Courtesy

    Vow was moving toward approval last year for its cultivated quail meat, dubbed Morsel. It had anticipated an end-of-2022 launch into Singapore restaurants, but it has yet to be approved by Singapore Food Agency (SFA).

    The mammoth meatball debut comes as the U.S. FDA issued a “no questions” letter to California’s Eat Just for its cultivated Good Meat label chicken. Eat Just is currently the only cultivated meat producer in the world with regulatory approval, which was granted by the SFA in 2020.

    Eat Just and fellow Californian cultivated meat producer Upside Foods, which received FDA clearance last November, now must both pass USDA inspections before they can begin selling their meat in the U.S.

    The post Vow Debuts Cultivated Meat Made From Extinct Wooly Mammoth DNA appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 3 Mins Read

    The Biden-Harris Administration revealed new priorities detailed in a report last week that will trigger actions to advance American biotechnology and biomanufacturing.

    The move follows an Executive Order signed by President Biden last September aimed at advancing biotechnology and biomanufacturing innovation. The goals aim to enhance America’s bioeconomy, restore local supply chains, and support the country’s innovation ecosystem.

    U.S. biomanufacturing

    Biomanufacturing, the use of biological systems to produce goods and services at a commercial scale, the tech has the potential to unlock sustainable alternatives across industries such as plastics, fuels, and medicines, the White House said in a statement. These innovations hold potential for new solutions in health, climate change, energy, food security, agriculture, supply chain resilience, and national and economic security.

    The White House Office of Science and Technology Policy (OSTP) detailed its plan in a new report outlining a vision for what is possible with biotechnology and biomanufacturing and the research and development needed. The report includes sections authored by federal departments and agencies that are responsive to the President’s E.O. on biotechnology and biomanufacturing R&D to further societal goals such as climate change solutions, food and agricultural innovation, supply chain resilience, human health, and crosscutting advances. These goals serve as a guide for public and private sector efforts to harness the full potential and power of biotechnology and biomanufacturing to develop innovative solutions in different sectors.

    lab worker
    Photo by Julia Koblitz via Unsplash

    The Department of Defense’s (DoD) Biomanufacturing Strategy will guide investments in bioindustrial domestic manufacturing infrastructure to establish a domestic bioindustrial manufacturing base. The strategy includes three priorities: establishing customers that stand to benefit from early-stage innovations, advancing biomanufacturing capabilities through innovation, mapping and tracking the biomanufacturing ecosystem to support future efforts. DoD is issuing a formal request for information on biomanufactured products and process capabilities that could help address defense needs and whose development and commercialization could be addressed by DoD investment.

    The Department of Commerce’s Bureau of Economic Analysis will assess the feasibility of economic contributions to the country’s bioeconomy, as called for in the President’s E.O. Other deliverables from the E.O. are also in development, including plans to expand training and education opportunities for the biotechnology and biomanufacturing workforce, a report on data needs for the bioeconomy, a national strategy for expanding domestic biomanufacturing capacity, actions to improve biotechnology regulation clarity and efficiency, and a plan for strengthening and innovating biosafety and biosecurity for the bioeconomy.

    ‘Accelerating the transition to a more sustainable and resilient food system’

    Magi Richani, CEO of Nobell Foods, a biotech company making animal-free cheese, applauded the move in a statement shared to LinkedIn. “I can’t overstate the importance of this step in accelerating the transition to a more sustainable and resilient food system,” she wrote.

    “Our global food system over the last few years has proven to be anything but resilient. And with the continued environmental degradation caused by industrial-scale animal agriculture, it’s not only refreshing, but critical to see the work we are doing prioritized as a key solution to building a more resilient food system, increasing consumer choice, and offsetting greenhouse gas emissions,” Richani said.

    Methane emissions
    Photo by Joachim Süß on Unsplash

    Richani pointed to animal agriculture, which contributes close to 31 percent of total U.S. methane emissions — a planet-heating gas more potent than CO2. But the reality is, she said, “no one will change their behavior fast enough to offset its impact. Most people are not going to eat less cheese or meat if it costs more or tastes less.”

    The U.S. investment into biotech could help change that. “The bold goals and R&D needs outlined in this report serve as a guide for public and private sector efforts to harness the full potential and power of biotechnology and biomanufacturing to develop innovative solutions in different sectors, create jobs at home, build stronger supply chains, lower costs for families, and achieve our climate goals,” the White House said.

    The post The White House Issues Guidelines to ‘Harness the Full Potential and Power of Biotechnology’ appeared first on Green Queen.

  • 3 Mins Read

    The CEO of cultivated pork startup New Age Eats announced in a social media post that the company is shutting down after just under 5 years of operation.

    Founder and CEO Brian Spears broke the news on social media writing that “we made the painful decision to shut down New Age Eats” amidst a tumultuous funding environment and a lack of runway to continue.

    “As the CEO, I take ultimate responsibility for this shutdown. When we started ~5 years ago, we had no blueprint to develop and commercialize cultivated meat. I am grateful to everyone who supported our brilliant, talented team as we learned along the way,” he said.

    Earlier this year, Spears penned another social media post in which he shared that New Age Eats was letting go of the company’s pilot manufacturing facility in the Bay Area’s Alameda city food innovation hub, The Research Park at Marina Village and asked potential buyers to reach out. “Construction is 90% complete (put your final touches on it!) and 80% paid for (we’re walking away from significant investment because, well, we have to). You’d be move-in ready in 1-2 months…We will take the best offer in the next few weeks!”

    Spears confirmed today the company was unable to find a buyer for the plant and was not able to secure additional funding: “Unfortunately, with recent capital market turmoil, we have been unable to attract investment.” He told AgFunder News earlier today that things changed starting the second quarter of last year: “The shift in capital markets beginning around spring 2022 has made life challenging for startups across the board, he said.”

    New Age Eats was focused on bringing cultivated pork sausages to market and had raised over $32 million dollars since its founding in June 2018 and backers included seasoned food and tech VCs like IndieBio, TechU Ventures and Siddhi Capital. The company reeled in a $25 million Series A investment round back in October 2021 led by South Korean energy and real estate conglomerate Hanwha Solutions and at the time had been vocal about a launch plan that included both the US and Asia.

    Spears was hopeful about the state of the cultivated meat sector going forward, writing that “While our company will no longer survive, multiple companies will pick up the baton and use our technology to further our shared mission.”

    He was candid about the challenge of creating a cultivated meat company and alluded to how complicated it was to match investment timelines in a R&D context that requires long timelines: “Creating the experience of meat without slaughter is extremely difficult. We start with biotech borrowed from human health applications designed for high cost, low volume products. We worked to flip to low cost, high volume products. That is expensive, takes time, and needs a lot of patient capital.”

    Spears also expressed his gratitude for all the support the company has received to date. “Lastly, I want to express profound gratitude to everyone who supported me and the team along the way. I’m also grateful to those who worked against us. Without them, I wouldn’t have learned what I did, that everything is one – no crest without trough, buyer without seller, villain without victim. My gratitude is for everything in this beautiful existence that we share. Ideally, my future work leads to broadly sharing that increased appreciation.”

    Spears has been outspoken about the importance of focusing on founder mental health and in his latest post, he said he was encouraged that this topic was gaining more attention: “The toll on my mental heaIth to gain these perspectives over the years has been tremendous. I am encouraged that mental health – including of founders – is being more openly discussed.”

    The post Cultivated Pork Startup New Age Eats Shuts Down After Five Years Amidst ‘Recent Market Turmoil’ appeared first on Green Queen.

    This post was originally published on Green Queen.

  • malaysian meal
    3 Mins Read

    Slated to launch in Q4 2024, Cell AgriTech says its first cultivated meat production facility will also be Malaysia’s first.

    Cell AgriTech says it plans to be in full production by spring of 2025, pending regulatory approval for cultivated meat. The company made the factory announcement during the first Malaysia Cultivated Meat Conference held at the Kuala Lumpur Convention Center earlier this month.

    Malaysia’s first cultivated meat facility

    “We are proud to be the first cultivated meat company in the country, bringing a sustainable and delicious alternative to traditional meat products,” said Jason Ng, the founder and manufacturing vice president of the Cell AgriTech group of companies.

    eel
    Photo by David Clode on Unsplash

    Cell Agritech’s focus will be on seafood, with tuna and eel up first. The goal is to achieve price parity with conventional seafood, the company says. The new facility will span three to four acres in size, with a 1,000-liter production volume.

    According to Deputy Science, Technology and Innovation Minister Datuk Arthur Joseph Kurup, who was also present at the conference, the global cultivated meat market is expected to grow from US$176.48 million (RM791.87 million) in 2022, to US$321.71 million (RM1.44 billion) in 2027.

    “The development of cultivated meat technology in Malaysia promises to create job opportunities and revenue while addressing national challenges such as food security, health management, and climate change,” Kurup said.

    Cultivated meat is currently only approved for sale in Singapore, but two U.S. companies, Eat Just’s Good Meat and Upside Foods, have received FDA clearance with “no questions” on their tech.

    Alternative protein across Southeast Asia

    In a post shared on LinkedIn, the Good Food Insitute APAC said the historical development also opens up opportunities for new collaborations across Southeast Asia. That kicked off with Ng announcing that Cell AgriTech will partner with Singapore’s Umami Meats to scale up the production of cultivated seafood.

    fish ball
    Courtesy Umami Meats

    Last year, Umami Meats announced it had produced cultivated fish cakes and filets, following the launch of cultivated fish ball laksa last August. It filed a patent for a novel single-stem cell technology that it says can build both muscle and fat in cultivated seafood.

    Mohd Khairul Fidzal Abdul Razak, CEO of the Bioeconomy Corporation — the lead development agency for the bio-based industry in Malaysia — said that as the global population surpassed 8 billion last November 2022, the cultivated meat industry is “poised to grow substantially.”

    “We believe that the future of meat is cultivated,” Ng said. “We are committed to bringing this innovative and sustainable solution to the meat industry as our focus in the field of cellular agriculture.”

    The post Malaysia Gets Its First Cultivated Meat Facility appeared first on Green Queen.

    This post was originally published on Green Queen.

  • cabbage looper caterpillar

    3 Mins Read

    Spain-based Cocoon Bioscience has closed a €15 million equity funding round to scale its looper moth-based tech, including the development of a new production facility in Spain.

    The new funding for the biotech startup spin-off of biotech company Algenex was led by Columbus Venture Partners and Cleon Capital with participation from Viscofan, and North South Ventures, among others.

    Caterpillar bioreactors

    Cocoon is focused on developing growth factors for cultivated meat and other alternative protein as well as mRNA synthesis and genetic sequencing. It uses looper moth caterpillars to develop its vaccines and growth mediums instead of steel bioreactors. It injects the moth cocoons with the Baculovirus and then encodes it with different information.

    Cocoon Bioscience CEO Josh Robinson
    Cocoon Bioscience CEO Josh Robinson | Courtesy

    “It’s kind of like leveraging cocoons as natural, low-cost bioreactors,” Cocoon Bioscience CEO Josh Robinson told AgFunder News. “When [humans] catch a virus like a flu, we make a bunch of mucus. Similarly, these moths catch this virus Baculovirus and make whatever protein or enzymes are sequenced into that virus,” he says.

    “We have a product, we’re selling it today, we just need to make more of it,” Robinson said. “We’re selling it at a price point that’s already lower than anyone else, and this platform develops new products extremely quickly.

    The new production facility will be located in Bilbao, Spain — about 250 miles north of Madrid — and is slated to be fully operational in 2024.

    “Our proof of concepts, from knowing what we want to make to having a sample ready to test is an 8- to 10-week process.”

    Reducing cultivated meat costs

    Robinson says that growth factors for cultivated meat costs hundreds of dollars for milligrams, but Cocoon’s tech takes away the bioreactor expense.

    GOOD Meat cultivated chicken
    GOOD Meat cultivated chicken | courtesy Eat Just

    But with companies moving away from animal-based growth mediums like fetal bovine serum, time will tell if there’s a market for moth-grown media. It’s not slowing things down for Cocoon, though.

    According to Robinson, 2023 is expected to be a big year for the company including building and completing the industrial-scale manufacturing facility “where we’ll be able to produce kilograms to tens of kilograms of these growth factors as well as these enzymes to meet scaling demand for our current partners and those that have expressed interest in working with us,” he said.

    “Cultivated meat companies need to manufacture whatever meat they’re producing in large-scale bioreactors,” says Robinson. “But the growth factors, those high-value, hero ingredients, have to program the bovine cells to perform the way they need to. Those growth factors are traditionally produced in bioreactors, and it becomes really expensive if you’re doing that in the traditional way.”

    The post Cocoon Bioscience Raises €15 Million for Its Caterpillar Bioreactors appeared first on Green Queen.

  • good meat

    4 Mins Read

    Good Meat, the cultivated meat division of Bay Area food technology company Eat Just, has received a “no questions” letter from the U.S. Food and Drug Administration for its cultivated chicken.

    The FDA has accepted Eat Just’s conclusion that its first poultry product, cultivated chicken, is safe to eat, clearing a crucial step in bringing GOOD Meat to restaurants and retail in the U.S.

    ‘No questions’

    The “no questions” letter comes as part of one of the agency’s first pre-market consultations for meat, poultry, and seafood made from cells instead of conventionally raised animals. It followed a similar clearance for fellow Bay Area producer Upside Foods that came from the FDA late last year.

    Good Meat’s cultivated chicken was the first in the world to earn regulatory approval, which was granted by the Singapore Food Agency in 2020. Good Meat won several regulatory approvals for its chicken in Singapore since 2020; it remains the only cultivated meat producer in the world with the ability to sell to consumers.

    José Andrés
    Chef José Andrés will be first in the U.S. to serve cultivated chicken | Courtesy

    “Today’s news is more than just another regulatory decision – it’s food system transformation in action,” Bruce Friedrich, president of The Good Food Institute, said in a statement. “Good Meat has become the second cultivated meat company to receive the go-ahead from FDA for its cultivated chicken, bringing cultivated meat closer to becoming a real choice for American consumers. Consumers and future generations deserve the foods they love made more sustainably and in ways that benefit the public good – ways that preserve our land and water, that protect our climate and global health, ways that allow for food security. Global demand for meat is projected to increase significantly by 2050. A few governments around the world are beginning to prioritize alternative proteins as a solution that accounts for this growing consumer demand while also achieving national climate and development goals, but far more need to follow suit.”

    Since its launch, Good Meat’s chicken has been featured on menus across Singapore including at fine dining establishments, hawker stalls, via the foodpanda delivery platform, and at Huber’s Butchery, one of Singapore’s premier producers and suppliers of high-quality meats.

    The company is now working with the U.S. Department of Agriculture on necessary approvals before world-renowned chef and humanitarian José Andrés is slated to become the first in the country to offer Good Meat’s chicken to customers at his restaurant in Washington, D.C.

    “The future of our planet depends on how we feed ourselves…and we have a responsibility to look beyond the horizon for smarter, sustainable ways to eat. Good Meat is doing just that, pushing the boundary on innovative new solutions, and I’m excited for everyone to taste the result,” Andrés said in a statement.

    Imminent regulatory approval

    The recent green lights from the FDA for both Good Meat and Upside Foods signal that the cultivated meat industry could be up and running in the U.S. within the next year or two. The U.S. requires a two-pronged approval process for cultivated meat involving both the FDA and the USDA. Experts predict cultivated meat could become a $25 billion global industry by 2030.

    Good Meat claims that surveys conducted on its cultivated chicken show a wide approval rating in Singapore with 70 percent of respondents who tried it claiming it tastes as good as or better than conventional chicken. Nearly 90 percent said they would opt for the cultivated chicken instead of conventional, and nearly as many restaurants said they would be open to selling the meat.

    Good Meat's cultivated lab meat
    Good Meat’s cultivated lab meat | Courtesy

    The benefits of cultivated meat are significant, especially when produced with renewable energy, according to a recent LCA. It has the potential to address many of the challenges associated with traditional meat production, including environmental concerns, animal welfare, and public health.

    “While I will always support family farmers’ efforts to feed the world, forward-thinking companies like Good Meat are tackling food security, nutrition and environmental stewardship in new and exciting ways,” said Dan Glickman, Good Meat Advisory Board member; former U.S. Secretary of Agriculture and member of the U.S. House of Representatives. “Receiving a ‘no questions’ letter from the FDA and a subsequent clearance from the USDA will allow Good Meat to scale up manufacturing and begin introducing its products to American consumers,” he said.

    “Just as the United States has been a global leader in modernizing conventional food and agriculture techniques, it too can lead in the emerging alternative protein space. Today’s announcement is one such example.” 

    The post BREAKING: Eat Just’s Cultivated Good Meat Is the Second to Receive FDA Clearance appeared first on Green Queen.

  • jimi chicken
    3 Mins Read

    The innovation and AI-driven Jimi Biotech has presented the first fully developed cultivated meat in China.

    China-based Jimi Biotech has achieved a major milestone in cultivated meat by developing what it says is the country’s first 100 percent cell-based meat. The product is created entirely from animal cells without any plant scaffolding.

    Zhehou Cao, CEO of Jimi Biotech, says that cultivated meat containing plant scaffolding cannot replicate the taste and product perception of real meat products, making 100 percent cell-based meat a more viable option for consumers looking for a sustainable option without sacrificing taste or texture.

    Cultivated chicken

    The company is working to develop what it calls “new forms” of meat while reducing public health risks and addressing food safety, environmental pollution, and animal welfare problems related to conventional meat production.

    jimi biotech chicken
    Jimi Biotech’s cultivated chicken | Courtesy

    Roosters in Hangzhou provided the cells for the meat. Cao said a sensory evaluation of the product found that the difference in color, smell, and taste comparing conventional chicken with Jimi’s cultivated chicken was minimal, making it a successful first attempt and a viable contender for scaling up, once China greenlights cultivated meat.

    The company says it has managed to reduce the cost of the culture medium to around ¥ 100 ($14), which is only 3 percent of the price of the culture medium on the market.

    Funding the future of sustainable meat

    Prior to the launch, Jimi Biotech completed its second exclusive ¥10 million round of funding ($1.45 million) in the last four months — both led by Shiwei Capital. The funding will be used for research and development as well as the construction of a small pilot plant.

    Weichang Jiang, a partner at Shiwei Capital, praised Jimi Biotech’s rapid progress in core areas such as cell lines and culture media. Jiang also noted that the company’s automation and AI will make the company an efficiency leader in the sector.

    jimi
    Jimi’s cultivated meat | Courtesy

    “Although only three months have passed since the last round of funding, Jimi Biotech has still made significant technological breakthroughs,” Jiang said in a statement. “In addition to the rapid progress in core areas such as cell lines and culture media, we believe that Jimi Biotech’s deep integration of automation and AI into the research and development also reflects the founder’s emphasis on continuously improving research and development efficiency.”

    The debut comes as the Chinese government has explicitly listed cultivated meat as a key area for future food manufacturing in the “14th Five-Year Plan” for National Agricultural Science and Technology Development. The National Food Safety Risk Assessment Center (CFSA) will also establish a special group for cultivated meat this year to study the regulatory framework of cultivated meat in China.

    “China has the largest market for meat and a well-established supply chain system, so we believe that some of the world’s leading cultivated meat enterprises will be Chinese enterprises,” Jiang said. “With the attention of the regulatory agency, the industry is about to enter an important turning point in China.”

    The post Jimi Biotech Debuts China’s First Cultivated Chicken appeared first on Green Queen.

    This post was originally published on Green Queen.

  • TurtleTree has debuted its cultivated lactoferrin
    3 Mins Read

    TurtleTree, a global leader in animal-free functional dairy proteins, has announced the launch of the world’s first precision fermentation-produced lactoferrin.

    Known as “pink gold” for its high value and iron-rich pink hue, Singapore-based TurtleTree debuted the cultivated LF+ product at an exclusive tasting event in San Francisco this week.

    LF+ is considered a highly prized bioactive milk protein and one of the most powerful components found in cow’s milk, with functional benefits for immunity, iron regulation, and digestive health.

    ‘Harnessing the power of precision fermentation’

    “By unlocking access to one of the most powerful and multifunctional proteins in milk, we are envisioning a better food future where more people than ever before can improve their personal nutrition sustainably,” TurtleTree Founder and CEO Fengru Lin, said in a statement. “Harnessing the power of precision fermentation will provide us with an abundant supply of these vital nutrients that can be enjoyed by all segments of the population through everyday food products.” 

    TurtleTree's lactoferrin
    TurtleTree’s lactoferrin in application | Courtesy

    TurtleTree says its breakthrough provides an affordable source of lactoferrin; conventional sources can retail at between $700 to $1,500 USD per kilogram.

    While lactoferrin is in use in supplements and infant formulas, supply scarcity means that demand cannot be met for other fertile segments like sports nutrition, where the protein’s iron-regulating benefits can improve physical performance.

    TurtleTree’s development is also removing high methane-emitting cows from the supply chain. Animal agriculture represents more than 15 percent of anthropogenic emissions, fueling the climate crisis.

    ‘Transforming the food system’

    “As one of TurtleTree’s early investors, KBW Ventures recognized that transforming the food system requires studied innovation; a commitment to the science, and both ingenuity and integrity to see it through,” said KBW Ventures Founder and CEO Prince Khaled bin Alwaleed.

    “Transforming the food system as a mission is the business of changemakers, and I am proud that we could play a role in fueling the world’s future in food. TurtleTree’s world first, the showcase of LF+, is what technology can do when mobilized for good,” he said.

    TurtleTree raised $30 million in a 2021 Series A funding round led by Verso Capital after it first announced the lactoferrin product was in the works in June 2020.

    Prince Khaled Bin Alwaleed was an early investor in TurtleTree | Courtesy

    “We are incredibly touched by the degree of faith all our investors have placed in TurtleTree and our unique vision of food,” Lin said at the time. “The Series A funds will allow us to scale up our processes and come a huge step closer to creating a new era of sustainable nutrition.”

    The company sees a clear path to profitability on a per unit basis within six to 12 months after commercial launch, which is anticipated for Q4 2023.

    Good Food Institute co-founder and president Bruce Friedrich called the development “another innovative breakthrough” that he says gives consumers more sustainable food choices and creates a more sustainable food system.

    “Consumers deserve nutritious, affordable options that are produced in efficient, better-for-the-planet ways,” Friedrich said. “With more private sector and public sector support, precision fermentation is one of the brilliant alternative protein technologies that can open up a world of possibilities on this front.”

    The post TurtleTree Debuts Its Cultivated ‘Pink Gold’ Lactoferrin appeared first on Green Queen.

    This post was originally published on Green Queen.

  • GOOD Meat cultivated chicken
    3 Mins Read

    A new ex-ante life-cycle assessment looks at the efficiencies and benefits of cultivated meat.

    The LCA looked at cultivated meat from more than 15 companies, comparing the outlook of cultivated meat production in 2030 to that of conventional animal meat. The research was funded by GAIA, The Good Food Institute, a donor-backed 501(c)3 nonprofit, and CE Delft. The findings are published in The International Journal of Life Cycle Assessment.

    “Cultivated meat (CM) is attracting increased attention as an environmentally sustainable and animal-friendly alternative to conventional meat,” reads the abstract. “As the technology matures, more data are becoming available and uncertainties decline.”

    The findings

    According to the researchers, the ex-ante LCA looked at cradle-to-gate production of 1kg of meat. Source data include lab-scale primary data from five cultivated meat producers, full-scale primary data from processes in comparable manufacturing fields, data from computational models, and data from published literature.

    “Although animal products contribute around 18 percent of calories and 37 percent of protein to the average global diet, the impacts on the environment are disproportionately large compared to non-animal products in diets (Poore and Nemecek 2018),” note the researchers.

    Photo by Louis Reed at Unsplash.

    The researchers note that conventional animal products’ impact on climate change is significant, making up between 16.5 percent and 19.4 percent of total anthropogenic greenhouse gas emissions, twice as large as plant-based sources and “by far the highest contributor within food system emissions.”

    Conventional animal products use approximately 83 percent of global agricultural land, including pastures and cropland for feed, as well as 41 percent of green and blue water use.

    The findings suggest cultivated meat is nearly three times more efficient at turning crops into meat than even the “most efficient” livestock, making agriculture land use significantly lower. It also found nitrogen emissions to be lower because of cultivated meat production efficiency and lack of manure.

    Renewable energy

    The report also points to the need for renewable energy in producing cultivated meat as the process is “energy-intensive”.

    “Using renewable energy, the carbon footprint is lower than beef and pork and comparable to the ambitious benchmark of chicken,” reads the report. “Greenhouse gas profiles are different, being mostly CO2 for CM and more CH4 and N2O for conventional meats. Climate hotspots are energy used for maintaining temperature in reactors and for biotechnological production of culture medium ingredients.”

    Cultivated chicken from Upside Foods
    Cultivated chicken from Upside Foods | Courtesy

    The researchers say cultivated meat producers should work to optimize energy efficiency, including sourcing renewable energy, and leverage supply chain collaborations to ensure sustainable feedstocks. The LCA also calls on governments to consider the renewable energy demands of the emergent cultivated meat industry, and, it encourages consumers to look at cultivated meat not as an extra menu option, but a substitute for higher-impact meat products.

    Cultivated meat has the potential to have a lower environmental impact than ambitious conventional meat benchmarks, for most environmental indicators, most clearly agricultural land use, air pollution, and nitrogen-related emissions, the researchers say. “While CM production and its upstream supply chain are energy-intensive, using renewable energy can ensure that it is a sustainable alternative to all conventional meats.”

    The post Life-Cycle Assessment Shows Cultivated Meat’s Benefits for a Sustainable Food System appeared first on Green Queen.

    This post was originally published on Green Queen.

  • burger
    3 Mins Read

    South Korea’s plant-based food manufacturer Pulmuone and cell-based startup Simple Planet have teamed up to co-produce hybrid cultivated meat.

    Pulmuone and Simple Planet say they’re working to co-develop and commercialize hybrid cultivated meat products that combine plant-based ingredients and cultivated meat. The companies are targeting a 2025 retail launch given the current lack of regulatory approval for cultivated meat products.

    Hybrid meat

    Demand for healthier and more environmentally friendly food is on the rise in South Korea; the country’s alternative meat market was worth approximately $15.6 million USD in 2022, an increase of 28 percent from the previous year, according to Euromonitor. The market is predicted to rise to $24 billion USD by 2025.

    simple planet
    Simple Planet’s cultivated meat will be blended with Pulmuone’s plant-based ingredients. Courtesy

    The move builds on Pulmuone’s recent launches including a plant-based meat brand last year and a 2020 partnership with cultivated seafood startup BlueNalu.

    Last June, Simple Planet announced that it had developed cultivated meat with a higher concentration of unsaturated fatty acids.

    Coldplay-backed SCiFi Foods is also working to develop plant-based and cultivated meat hybrids.

    Hybrid meat development is also coming to conventional meat producers. Last month, Mush Foods announced its mycelium protein intended for combining with traditional beef.

    U.S. market

    Pulmuone is also preparing to increase its U.S. presence. Already, 70 percent of the tofu products sold in the U.S. are made by Pulmuone; Walmart, Costco, and hundreds of restaurant chains currently use Pulmuone’s products. It’s the company behind the Plantspired range.

    The company is now aiming to bring healthy, low-fat Korean food sold in South Korea for the last 40 years, to the U.S. consumer, including a range of “healthy” instant noodles.

    Cho Kil-su, head of Pulmuone, told the Korean Herald that the U.S. market saw significant growth in consumption of plant-based food after the pandemic years, as consumers’ interest in health grew.

    plantspired
    Pulmuone is behind the U.S. brand Plantspired. Courtesy

    “Concern for the environment also grew after the pandemic, and demand for plant-based products soared even higher as they produce less carbon dioxide throughout the production process,” he said.

    “This year, we plan to further expand our production infrastructure and expand our B2B business. We will mainly center on supplying universities with our products, as we have analyzed that young adults are most sensitive about health issues and receptive to new types of food,” said Cho.

    “We have partnered with leading local universities such as Yale University and Virginia Tech to provide sustainable food, and contribute to having students establish healthy diets.

    “We also aim to foray into Canada and Europe by expanding our tofu production line at the Ayer tofu plant (in Massachusetts) at the end of 2023.”

    Fellow South Korean plant-based food manufacturer Unlimeat has also seen steady growth in the U.S. after launching in stores last year. It recently launched its plant-based Korean BBQ and two flavors of pulled pork into 1,500 Albertsons locations.

    The post South Korea’s Tofu Giant Teams Up With Cultivated Meat Startup Simple Planet appeared first on Green Queen.

    This post was originally published on Green Queen.

  • Jellatech collagen
    3 Mins Read

    The jury’s still out on whether or not collagen supplements have any real benefits, but as an investigation links the industry to deforestation, an achievement from Jellatech may bring new opportunities to the booming category.

    In a post shared on LinkedIn, the North Carolina-based biotech startup Jellatech announced it has created a fully functional human collagen made from a proprietary cell line.

    ‘An important step’

    The announcement comes just eight months after the company debuted its cell-based bovine collagen. Human collagen is used in biomedical and clinical applications including tissue engineering, arthritis treatment, regenerative medicine, 3D bioprinting, and dermal fillers, among other applications.

    Courtesy, Jellatech

    “This milestone further demonstrates that our platform technology for efficiently producing high quality collagen is translatable across multiple cell types, which allows us to address a broad market need for collagen,” Rob Schutte, Jellatech’s head of science, said in the post.

    Stephanie Michelsen, Jellatech’s founder and CEO, praised the achievement, calling it “an important step” in the company’s commitment to making a positive impact.

    Collagen and deforestation

    The announcement comes as a new investigation links the demand for collagen, a popular supplement purported to have wellness and beauty benefits, to deforestation in Brazil. Collagen is typically sourced from cows, but can also come from pigs and fish.

    According to findings from the Guardian, Bureau of Investigative Journalism, Center for Climate Crime Analysis (CCCA), ITV and O Joio e O Trigo, collagen traced to the popular Jenifer Anniston-backed Vital Proteins brand owned by food giant Nestlé, is connected to Amazonian deforestation.

    CJulian Peter via Pexels

    The investigation found tens of thousands of cattle raised for collagen production are on farms linked to tropical deforestation — an ongoing crisis contributing to climate change and biodiversity loss. Eighty percent of the Amazon’s deforestation is connected to the livestock industry.

    The Guardian reports that, unlike beef, soy, and palm, among other food commodities bound to due diligence legislation over deforestation links, the collagen industry sits outside of these regulations and has no obligation to disclose connections.

    Nestlé told the Guardian the allegations don’t align with its responsible sourcing commitments and it has taken steps to ensure its products are “deforestation-free” by 2025.

    Despite the demand for animal collagen, research into its benefits is lacking. The Guardian reported that Harvard School of Public Health cautioned consumers over study findings as most “if not all” of the research has been funded by industry members or scientists affiliated with stakeholder brands.

    Unbiased research, however, has pointed to the benefits of consuming collagen-building foods, rather than consuming collagen itself. Foods such as those rich in vitamin C, zinc, copper, silicon, and the amino acids lysine and proline, have all been linked to healthy collagen production.

    The post Jellatech Debuts Cell-Based Human Collagen As Investigation Links Industry to Deforestation appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 12 Mins Read

    No single approach will offer a silver bullet solution to all problems within the food system — no matter how large the opportunity or dire the need.

    When expectations exceed reality, outcomes that may normally be considered successes are seen as failures. I’ve been witnessing the disconnect between expectations and reality in sustainable food for a while now.

    On one side, there’s the pitch that individual startups will save the planet and take over the multi-trillion dollar industrial animal agriculture industry along the way. This side pitches the idea of food companies growing in ways only seen in the tech space, since the need is so dire and the opportunity for disruption is so massive. This has inevitably led to food startups being valued like tech startups, with expectations that the size and rate of growth will be immense.

    On the other side, there’s the reality that regardless of the amount of R&D, IP, or clever marketing tactics, all of these companies are simply producing food for people to eat. They take different amounts of time and money to scale, and they should be valued like….food companies. Maybe a premium can be applied to some with exceptional solutions to certain problems, but they are still food companies.

    Recently Beyond Meat has been painted to have lost $13 billion dollars of value; however, I would argue that it never should have been valued that highly in the first place. Historically, CPG food companies are valued between 2–5x revenues. There are outliers to that, but generally, 2–5x is the norm. Knowing this, it’s clear that at a $14 billion market cap, which was over 35x revenues, Beyond Meat was highly overvalued.

    Public market investors had expectations that were not based on reality. The reality is that Beyond Meat is a CPG food company generating ~$450M a year in revenue and selling food for consumers to eat. With 2–5x revenue being the norm, it is reasonable to expect Beyond Meat to trade at a market cap between $900M and $2.3B. If some want to price in rapid growth, then going a bit above $2.3B could make sense, but it’s hard to argue a 35x+ revenue multiple being grounded in reality.

    Now imagine the perception of Beyond if the story went like this: Beyond Meat IPOs at $800M and steadily grows its market cap to $1 billion. Retail investors who bought in early are now up 25%+, and the decisions by the company to focus on profitability are welcomed in the difficult broader macro-economic environment that’s affecting all industries worldwide. Investors now feel quite positive about Beyond Meat as it goes from being a startup to a larger, more established CPG company.

    The Reality

    Today, Beyond Meat sits at ~$1 billion in market cap, representing an ~2.2x revenue multiple — right in the range of historical norms for CPG companies.

    Despite this valuation being more appropriate, the story of Beyond Meat is one of failure and loss for those with greater expectations. To them, it doesn’t matter that this small food startup became a billion-dollar organization. Instead, it is a major letdown.

    Now, when looking at other areas within the sustainable food ecosystem, the goal should be to set realistic expectations, so companies progressing our food system are not portrayed as meaningless failures.

    So how do current expectations in cultivated meat mesh with reality? Let’s talk about it.

    Big Things are Happening in Cultivated Meat

    After many years of splashy headlines and big promises, the cultivated meat space has recently seen some major progress. In 2022 alone, there seemed to be a new major event happening worldwide on a continual basis.

    Some developments to note are:

    1. January: San Diego-based cultivated seafood company BlueNalu collaborated with sushi restaurant operator Food & Life Companies to develop bluefin tuna for Food & Life Companies’ 1,000+ restaurants across Japan, South Korea, Taiwan, Hong Kong, Singapore, Thailand, and mainland China.
    2. February: One of Asia’s largest food and biotech companies, CJ CheilJedang, is entering the cultivated meat industry in partnership with KCell Biosciences, a startup focused on cell culture media. The companies will construct a cell culture media facility in Busan, South Korea.
    3. March: Israel-based SuperMeat announced a strategic partnership with large Japanese food manufacturing company Ajinomoto to pool R&D capabilities for the development of cultivated meat products.
    4. April: Mogale Meat and Mzanzi Meat develop Africa’s first cultivated chicken breast and beef burger, respectively.
    5. May: Israel-based cultivated meat company MeaTech 3D announced that its subsidiary Peace of Meat signed a strategic agreement with mycoprotein company ENOUGH to develop hybrid cultivated and fermentation-based products.
    6. June: China-based cultivated meat startup Joes Future Foods debuted China’s first cultivated pork belly at the New Technology Conference.
    7. July: Shiok Meats signs a partnership with Minh Phu Seafood, Vietnam’s largest conventional shrimp company, to develop a combined R&D facility focused on cultivated meat.
    8. August: Singapore-based Gaia Foods (a subsidiary of cultivated seafood company Shiok Meats) and Switzerland-based Mirai Foods have entered a strategic partnership to develop cultivated beef. The companies will collaborate on ingredients manufacturing and distribution, with plans to launch cultivated beef in Singapore and Switzerland.
    9. October: Vow Foods opened the largest cultivated meat facility in the southern hemisphere.
    10. November: APAC Cellular Agriculture signs MOU solidifying “cultivated” nomenclature.
    11. NovemberTasting of GOOD Meat at COP27.
    12. December: GOOD Meat’s cultivated chicken becomes the first cultivated meat to be sold in a butchery.

    *Thanks to our friends at The Good Food Institute for this list!*

    With all of this buzz, it feels as if this potentially game-changing solution may be in the mouths of US consumers soon. This felt even more feasible after the US FDA gave the green light to UPSIDE Foods’ cultivated chicken, showing signs of major regulatory progress required for the sale of cultivated meat.

    One additional announcement that caught major attention, including my own, was the move by Believer Meats to build the world’s largest cultivated meat plant in Wilson, North Carolina. This 200k square foot facility is expected to cost ~$124M to build (a fraction of the company’s most recent $347M Series B) and produce 10,000 metric tons of cultivated meat.

    This Feels like a Big Deal

    On an absolute basis, this is a big deal. Ten thousand metric tons of meat is a lot.

    To put this into perspective, consider the following:

    • 10k metric tons is equal to 11,023 US tons (because in the US, it’s always fun to make things make slightly less sense), or roughly 22M pounds (that’s a lot of chicken).
    • How many chickens exactly? Since the average broiler chicken is 6.46 lbs and accounts for 20% loss during processing, the average amount of meat per chicken is roughly 5.17 lbs. Therefore, Believer Meats would be saving the lives of 4.27M chickens annually with this one facility. To put that into perspective, if all of those chickens were their own city in the US, they’d make up the second-largest city in the country, only behind New York City.
    • As for feeding people, chicken consumption per capita in the US was at 100.6 lbs, meaning this facility could satisfy chicken demand for 219,147 people. That’s the same as feeding the entire city of Tacoma, Washington.

    Saving over 4M lives and feeding over 200k people would be quite the achievement.

    But What About the Financials?

    Believer Meats is far from a charity, and there have been many question marks around the economics of cultivated meat companies, especially given the large amounts of investment dollars they’ve raised.

    To understand what potential revenue from this plant could look like, we can apply a basic approach:

    • Start with current chicken prices, which sit at $2.72 per pound for chicken breast
    • Apply a premium to account for Believer Meats being one of the first companies in history to offer cultivated chicken to consumers. Picking this premium isn’t easy, but I’m making the assumption that much of the first chicken products created from this facility will be sold in high-end restaurants (or to consumers who can afford a major premium). If we apply a 5x premium, then we can assume Believer Meats is selling products for $13.60/pound. Maybe it will be higher, maybe it will be lower. I have no clue.
    • At $13.60/pound, and 22M pounds, that represents annual revenues of ~$300M

    That topline number of $300M from one facility can vary widely depending on the assumptions and the approach used by Believer. Pricing assumptions can be changed, and even slight changes in the expected inclusion rate of cultivated cells versus plant-based ingredients can drastically change the amount of product available for sale (i.e., 100% cultivated vs 50/50 cultivated/plant-based).

    $300M may be both a high or low estimate, but either way, the path to real dollar creation is much more tangible. Considering Believer Meats mentioned an ability to create chicken breast for $1.70, as well as ~$6M of annual salaries for plant employees, it also seems positive unit economics are not out of the question (though I am a bit skeptical on the $1.70 number).

    Additionally, while the company may have had to foot the bill for this first major facility, this will allow them to prove out the operations and economics of a cultivated meat facility, thus allowing them to tap into traditional capital market mechanisms for CAPEX financing needs for future builds (i.e., project finance/debt).

    So it looks like the end of industrial animal agriculture is here, and that the economics are on the side of cultivated meat, right?!

    Time to Reel In Those Expectations

    As amazing as these achievements are for an individual company, it’s just the very beginning for the space in terms of true impact on the food system.

    In terms of overall consumption, the Believer Meats production of 10k metric tons of chicken represents just 0.02% of the ~49M metric tons of meat produced in the US annually, and 0.008% of the ~133M metric tons of poultry produced globally.

    And that’s just the US meat and global poultry market for comparison. When we look at the overall meat space, that number jumps up to almost 350M metric tons plus another ~200M metric tons of seafood.

    Now if we assumed any cultivated meat facility could produce 10k metric tons of meat or seafood annually, then to fill the demand for the ~500M metric tons currently produced would require 50,000 facilities. At $100M per facility (~20% lower than the Believer Meats facility cost), that implies ~$5 trillion (with a “T”) of CAPEX costs for the facilities alone.

    Let’s also not forget that meat consumption is not static and is expected to rise dramatically over the next few decades to 555M metric tons (from the ~350M today). This 205M metric ton increase, alone, would require ~$2 trillion of CAPEX costs for the facilities (this doesn’t account for increased seafood consumption).

    To date, total investments in alt proteins over a 12-year time frame are sitting around $15B. At this rate of investment, it will take about 3,000 years to fund the CAPEX needed to create enough cultivated meat facilities that would replace industrial animal ag in its entirety.

    Yes, in reality, cultivated meat companies will be able to tap into traditional capital markets (i.e., project finance) once operations are more proven, so larger dollars will flow into the space faster.

    And yes, these are all projections with major assumptions, and “garbage in, garbage out.” So just for the sake of it, let’s say I’m off wildly on the $7+ trillion CAPEX need and cut it by 85%. That’s still $1 trillion of CAPEX needed.

    No matter how you look at it, the reality is that cultivated meat is not on the cusp of completely upending the traditional animal ag market.

    Industry Insiders Know This

    Every person I know in the cultivated meat industry is well aware this is only the beginning. There is not some false understanding from the sustainable food community thinking otherwise.

    So What’s the Issue?

    If industry insiders (i) know about the massive hurdles to be overcome in cultivated meat, AND (ii) that knowledge is widely shared with the public, expectations should be based on reality. This would also mean that no one will be disappointed with the progress of the cultivated meat space. Right?

    Wrong.

    The real problem that exists, resulting in widespread unrealistic expectations, is the portrayal of each sustainable food innovation as if it were the single, silver bullet solution to all issues facing the food system.

    This means each time any new potential solution is presented, it is examined in a silo. This silo shows what it will take for that single solution to solve all of the problems that exist, which unsurprisingly results in the new solution facing impossibly large hurdles.

    This first occurred with plant-based meat alternatives being portrayed as a silver bullet solution. When realism set in, it left the market viewing startups that turned into $1B+ organizations as failures.

    This framing can be applied to any form of sustainable food solutions with the same outcome. Whether it’s plant-based meat, precision fermentation, biomass fermentation, molecular farming, vertical farming, etc. — there is an endless list of sustainable food innovations that will all be presented with impossibly high hurdles to overcome if they are expected to be the one, silver bullet solution to the food system’s problems.

    The reality is that whether it’s plant-based meat or cultivated meat or precisions fermentation dairy, each of them is one of the many solutions needed to shift to a sustainable food system and it will serve its intended purpose — to reduce the reliance on industrial animal agriculture as the sole source of real, animal-based meat and seafood for those (i) not willing to give it up and (ii) open to eating products produced in this manner.

    The New Expectation

    Going forward, expectations for any sustainable food solution should be based on the reality that it will be one of many solutions filling a need in the food system. No single solution will take over the entire market, address every need, or attract every consumer. Instead, all solutions will collectively work together to take a bite out of the currently unsustainable multi-trillion-dollar global food system with the hope that they all help us reach a symbiotic relationship with the planet.

    Additionally, continual innovation will occur within each industry, allowing them to become better, more efficient, and more desirable to consumers. There will also be new innovations that emerge, unlocking entirely novel opportunities that could improve our food system further. Maybe these new innovations will address major hurdles in existing segments (i.e., growth media costs, bioreactor scalability, downstream processing costs, etc.) or create new categories entirely.

    As investors in the sustainable food space, we have seen first-hand how new innovations emerge over time, opening up entirely new opportunities. The types of companies and technologies in which we invest today are noticeably different than what we invested in back when the industry was first emerging. And, we fully expect to see opportunities five years from now being different from what we see today.

    The one timeless consistency is that each new innovation has the potential to help catalyze a shift to a more sustainable food system.

    Where Do We Go From Here?

    For cultivated meat, for example, the new expectation should be that it will likely be a smaller fraction of the overall animal agriculture market. How small? — That’s not clear. Maybe it becomes 1% by 2050 (5M+ metric tons) and there are only a handful of successful companies in the space owning a share of the $50B+ cultivated meat industry. Or, maybe It’s 10% (50M+ metric tons) and there are many successful companies owning a share of a $500B+ industry.

    A lot of that depends on continued innovation, cost reductions, and scale, but either way, the cultivated meat industry has a chance to be one of the many food system solutions our planet needs, while also creating a multi-billion dollar industry that does not currently exist.

    The same can be said about the myriad of potential solutions — they may all have a chance to be one of the many food system innovations we need with the potential to create meaningful impact and value. And none offer a silver bullet solution.

    Without question, hyperbolic statements will continue to be made making us think otherwise:

    • Startups will continue to make grand claims to attract investors
    • Investors will continue to hype up their portfolio companies
    • Activists and non-profits will continue to emphasize the urgency
    • And, reporters will continue to create clickbait headlines that are overly optimistic or pessimistic, because expectations based on reality are boring

    Despite this, reality will sit somewhere within all of this noise, so we must constantly remind ourselves that (i) many solutions are needed and (ii) the opportunity is so large that all solutions have the chance to create meaningful impact and value.

    A failure to shift our expectations will result in widespread disappointment and possibly lead to an underinvestment in innovations with legitimate potential for positive change.

    Set expectations, accordingly.

    A version of this article was previously published on Medium

    The post Expectations vs. Reality: It’s Time To Change The Investor Conversation Around Sustainable Food appeared first on Green Queen.

  • 3 Mins Read

    Dutch cultivated meat pioneer Mosa Meat has announced a partnership with its investor Nutreco to develop a cell feed supply chain.

    The Letter of Intent signed with Nutreco will support the development of a cell feed supply chain that can expedite production and scalability, Mosa Meat announced. Nutreco is an expert in developing sustainable feed solutions for animal agriculture.

    Food-grade cell feed

    The company’s scientists say they have successfully substituted more than 99 percent of the base cell feed by weight with food-grade ingredients marking an industry milestone for cultivated meat development. According to Mosa, it’s proof that producing high-quality cultivated meat with food-grade ingredients can be done at a lower price point.

    A burger made from Cultured Beef, which has been developed by Professor Mark Post of Maastricht University in the Netherlands. PRESS ASSOCIATION Photo. Issue date: Monday August 5, 2013. Cultured Beef could help solve the coming food crisis and combat climate change. Commercial production of Cultured Beef could begin within ten to 20 years. Photo credit should read: David Parry/PA

    “Our partnership with Nutreco represents our commitment to further develop the cellular agriculture supply chain and bring down costs,” Maarten Bosch, CEO of Mosa Meat, said in a statement. “Our scientific results are an industry first, proving that food-grade ingredients perform equivalent to pharma-grade in cell feed. This will represent a significant cost savings as we scale up production.”

    “At Nutreco, we innovate to produce feed ingredients more sustainably and create feed formulations optimised to deliver the highest yields for protein producers. Through our collaboration with Mosa Meat, we mastered a crucial step in creating affordable, food-safe and scalable nutritional solutions for the cultivated meat industry,” said Susanne Wiegel, head of the Alternative Protein Programme at Nutreco

    The announcement builds on a REACT-EU grant Mosa Meat and Nutreco received in 2021 for their collaborative Feed the Meat project aimed at reducing cultivated meat costs while also filling out the supply chain for scalability.

    Reducing media costs

    One of the main challenges of cultivated meat is the high cost of producing the cell feed — the nutrient-rich broth that cells are grown in. Mosa Meat says recent experiments saw fully maturing beef cells that were fed solely with food-grade substitutes — delivering similar cell density to cells fed with more costly pharma-grade material.

    Photo by Louis Reed at Unsplash.

    Mosa Meat is a pioneer in the cultivated meat category; in 2013, it unveiled the world’s first hamburger made from lab-grown meat, which cost €250,000 to produce. Since then, the company has been working on reducing the cost of producing cultivated meat to make it more affordable and accessible. In 2022, it published its technique for replacing the controversial growth medium, fetal bovine serum, in the journal Nature Food. It achieved that milestone without genetically altering cells.

    The post Mosa Meat’s New Cell Feed Supply Chain Will Bring Cultivated Meat Prices Closer to Conventional appeared first on Green Queen.

    This post was originally published on Green Queen.

  • Meatiply's cultivated duck meat
    3 Mins Read

    A new study suggests that there is a positive correlation between consumers’ psychological well-being and their willingness to consume cultivated meat.

    Researchers at Singapore Management University’s School of Social Sciences surveyed 948 Singaporean adults in June and July 2022 using an online questionnaire with the goal of examining the relationship between psychological well-being and their willingness to eat animal meat derived from cellular agriculture. The findings were published in the peer-reviewed journal Science Direct.

    This marks the first time that research has shown there is a positive relationship between a person’s psychological well-being and their willingness to consume cultivated meat. The results reveal that the increased willingness of the participants to eat cultivated meat can be further explained by a better understanding of the benefits of cultivated meat including its safety and its societal benefits.

    Higher well-being and willingness to eat cultivated meat are linked

    Professor Dr. Angela KY Leung, Ph.D., who co-led the study, told Green Queen that the general hypothesis they had when conducting the study was a positive correlation between psychological well-being and acceptance of cultivated meat. 

    Leung said well-being was defined as a positive mental state. “This has to do with people’s cognitive and affective evaluations of their life. The cognitive component concerns people’s appraisal or perception of life satisfaction, and the affective component concerns their emotional experiences (i.e., the experience of higher levels of positive emotions or lower levels of negative emotions).”

    Sample questions included: “In the past month, how often did you feel…(never to everyday)?” with participants able to choose between the following answers: Happy; Interested in life; Satisfied with life; That you liked most parts of your personality; That your life has a sense of direction or meaning to it.

    The researchers told Green Queen that while they were not very surprised by the findings, it was encouraging to see the research providing empirical evidence to support a positive relationship between people’s psychological well-being and their receptivity to the novel food of cultivated meat for the first time.

    Leung said: “It is also very insightful to find out why higher well-being people tend to have a more accepting attitude towards cultivated meat – their higher willingness is driven by the perception that cultivated meat is as healthy and nutritious, as safe as, and has the same sensory quality as conventional meat, and is beneficial to the society.”

    Marketing takeaways for cultivated meat companies

    When asked what cultivated meat companies and ecosystem players could take away from this research, Leung said that startups should focus on the well-being profile of their future consumers, target higher well-being individuals, and make use of information related to health and safety issues and societal benefits afforded by cultivated meat in their information campaigns and company materials.

    She added that they should also look at country happiness and well-being indices to focus their marketing efforts on geographies with a higher happiness index. “They can seek to first promote greater awareness of cultivated meat in these societies, and over time higher public acceptance can be picked up by other countries to make advocacy efforts more effective.”

    Leung said that cultivated meat companies should consider leveraging search advertising in their go-to-market strategies, targeting higher well-being consumers in ads and other digital marketing campaigns who are likely to perform online searches using keywords such as ‘healthy meat’, ‘safe meat’ and ‘environmentally friendly meat’.

    Asian consumers open to cultivated meat

    There is still very little research on consumer attitudes towards cultivated meat though separate studies conducted in Singapore and Hong Kong suggest Asians have a positive initial view of such products compared to Australians, with one study showing that Indian and Chinese people have a more favorable view of the technology than participants in the US. According to findings published last year, “food neophobia and uncertainties about safety and health seem to be important barriers to uptake of this technology.”

    The post Higher Well-Being Consumers Are More Willing To Consume Cultivated Meat, Shows New Research appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 3 Mins Read

    Israeli cultivated meat manufacturer Aleph Farms has announced the acquisition of a manufacturing facility in Modi’in, Israel, and related assets from biotechnology firm VBL Therapeutics, along with a new manufacturing agreement with ESCO Aster in Singapore.

    Aleph Farms says it’s moving closer to increasing its production capabilities with its two new arrangements in key markets. Israel ranks second globally in cultivated meat investments, and Singapore is currently the only country that has approved cultivated meat for sale and distribution.

    Aleph says it plans to bring its thin-cut steak grown from cells to market in both Israel and Singapore.

    A clear roadmap to scalability

    “Building up production capacity quickly in those locations while keeping capital investment lean provides a clear roadmap to scalability,” Didier Toubia, CEO, and co-founder of Aleph Farms, said in a statement. “Beyond Israel and Singapore, we plan on building additional strategic assets worldwide as part of our effort to bring more security and resilience to food systems.”

    aleph farms facility
    Aleph Farms’ 65,000-square-foot facility in Rehovot, Israel. Photography: Amit Goren

    Aleph Farms’ acquisition of VBL Therapeutics’ assets and technology transfer from its pilot production facility in Rehovot, Israel, will increase local output in response to the rising demand for quality protein, the company says. Dror Harats, MD, Chief Executive Officer of VBL, said its state-of-the-art facility will enable Aleph Farms to “unlock value and ramp up local production.”

    ESCO Aster is the world’s first and only company with full regulatory approval from a government authority to produce cultivated meat for commercial sales and consumption. It works with California’s Eat Just to produce its cultivated Good Meat, the only approved cultivated meat for sale in the world.

    Aleph Farms aims to be the second; it will work with ESCO Aster to expand production in Singapore. The partnership will enable the company to work towards its goal of establishing agri-food capabilities that can satisfy 30 percent of Singapore’s nutritional needs locally and sustainably by 2030.

    “We are proud to be working with Aleph Farms to bring its cultivated steak to Singapore,” said Xiangliang (XL) Lin, CEO of ESCO Aster and Deputy CEO of ESCO Lifesciences Group. “As part of our contract manufacturing MOU, we will work together with religious authorities on obtaining a halal certificate for our facility, enabling our collaboration with Aleph to expand to even more of the broader region.”

    Cultivated meat in Israel

    The demand for sustainable protein such as cultivated meat is on the rise globally as concerns about the food system continue to point to necessary shifts in the agricultural sector.

    Aleph Farms Cultivated Beef Steak
    Aleph Farms’ aims to bring its kosher-certified cultivated steak to market this year. | Courtesy

    According to a recent report by Meticulous Research, the cultivated meat market is expected to grow from $12.9 million in 2020 to $572.5 million by 2030. The report also notes that the Asia Pacific region is expected to grow at the highest CAGR due to the increasing demand for meat alternatives.

    Israel continues to be a leader in the cultivated meat category, according to a recent report from the Good Food Institute. The report notes a 130 percent increase in early-stage Israeli-alt protein companies between 2021 and 2022, and last year, Israeli-based cultivated meat companies raised more than $450 million — second only to the U.S.

    The post Aleph Farms Increases Its Cultivated Meat Capabilities With 2 Key Moves appeared first on Green Queen.

    This post was originally published on Green Queen.

  • Prime minister of japan fumio kishida
    3 Mins Read

    Japan’s Prime Minister Fumio Kishida says the country will move forward with a plan to develop an industry of “cell agriculture” bringing a focus to cultivated meat and fish as a means to reduce the country’s carbon footprint.

    Prime Minister Kishida is looking forward to creating a new agriculture sector that will increase the country’s sustainability he said in a statement.

    ‘A new market’

    “We will develop the environment to create a new market, such as efforts to ensure safety and the establishment of labeling rules, and foster a food tech business originating in Japan,” Kishida said.

    In his statement, Kishida emphasized the importance of supporting a sustainable food supply and contributing to solving the world’s food problems. He highlighted the potential of food tech, including cultivated meat, to create a new market and foster a food tech business sector in Japan.

    Cellular agriculture is currently seeing a boom in investments and developments despite lagging regulations outside of Singapore — currently the only country that has approved cultivated meat for sale and consumption. The U.S. recently granted its first GRAS status to cultivated chicken developed by California-based Upside Foods. But it must still clear USDA regulations before it can be approved for sale.

    GOOD Meat cultivated chicken
    Available in Singapore, GOOD Meat’s cultivated chicken is currently the only approved cell-based meat for sale. | courtesy Eat Just

    The regulatory framework around cultivated meat is also still evolving globally and Japan specifically has not yet approved cultivated meat or safety standards for raw materials and manufacturing processes have not yet been established.

    According to Japan’s Minister of Health, Labor, and Welfare Katsunobu Kato, “While paying close attention to the state of research and development, scientific findings on safety, and international trends, we will further consider what measures are necessary in terms of safety.”

    Food labeling on cultivated meat is another issue that needs to be addressed. Consumer Minister Taro Kono expressed his support for cultivated meat, saying, “I think cultured meat has a lot of potential. When the safety is confirmed and it hits the market, I’d like to make an effort to properly label it.”

    Cultivated meat’s global impact

    The development of cultivated red meat has the potential to significantly reduce the environmental impact of animal agriculture.

    Upside Foods has built a massive cultivated meat factory in California despite lagging regulations. Courtesy

    According to a study by the University of Michigan, lab-grown meat could reduce greenhouse gas emissions by up to 96 percent, land use by up to 99 percent, and water use by up to 96 percent, compared to traditional animal agriculture.

    At a House of Representatives Budget Committee Prime Minister Kishida told Nobuhiro Nakayama of the Liberal Democratic Party that food tech, including cellular foods, “is an important technology from the perspective of realizing a sustainable food supply. We have to support efforts that contribute to solving the world’s food problems.”

    Last year, Japanese cellular agriculture startup IntegriCuture closed a $ 7 million Series B funding round to develop affordable growth mediums and other tech solutions for the cultivated meat sector, with the aim of making its work open source so as to accelerate the sector’s commercialization. 

    The post Japan’s Prime Minister Embraces Cultivated Meat As Part of the Country’s Sustainable Future appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 4 Mins Read

    Good Food Institute Israel details the strength of the alternative protein market in Israel in a new ‘State of The Industry’ report.

    The new Good Food Institute Israel (GFI) report, entitled Israel – State of Alternative Proteins, showed that in 2022, Israeli startups raised more than $450 million in investments for alternative proteins, making it the second-largest country for alternative protein investments after the U.S.

    The findings

    Israeli companies accounted for approximately 15 percent of the total capital raised for the sector and 60 percent of all investments in Israeli food tech firms went to alternative protein startups. While the amount of investment in the industry decreased in 2022 from $623 million in 2021 to $454 million, GFI says Israel is still a key player in the global food tech market. Seed investments in alternative protein startups grew 130 percent in 2022, according to the report.

    The alternative protein sector in Israel includes plant-based substitutes for meat, dairy, and egg, cultivated dairy, meat, and seafood made from cells, and various fermentation processes and products using techniques.

    GFI Israel CEO Nir Goldstein said the global trend in 2022 was moving toward an “arms race” for alternative proteins, with countries such as China, France, the U.K., and Denmark making significant investments in the field. Goldstein said that while Israel could become a center for both R&D and industrial manufacturing, there’s every reason to emphasize regional manufacturing of food in order to further drive down the sector’s carbon footprint.

    Aleph Farms Cultivated Beef Steak
    Aleph Farms’ aims to bring its kosher-certified cultivated steak to market this year. | Courtesy

    “We have seen large countries follow along with President Biden in the U.S., who ordered to put together a strategy to bolster biotech, including alternative proteins,” Goldstein told The Times of Israel. “China has a five-year strategy, and smaller countries like the U.K. and Denmark have made significant investments, and this raises the question of what is the future of Israel after we got an edge now as a startup nation? Can we become a scale-up nation?

    “We believe that food needs to be manufactured as close as possible to where it is consumed for sustainability and economic reasons but Israel can definitely become a center for both R&D and industrial manufacturing,” Goldstein said.

    Israel ranks second to the U.S. in fermented proteins, attracting 18 percent of global investments with $147 million secured in 2022. In the cultivated meat subsector, Israeli companies drew more than $105 million in investments, accounting for approximately 12 percent of the total investment in the sector worldwide. In the plant-based alternative proteins sector, Israeli startups attracted $200 million in capital, or 16 percent of the global sector investment.

    Funding local startups

    According to GFI, local startups entered the alternative protein space last year, with four in the cultivated area, four in plant-based, and four in fermentation-derived products. Over the past two years, alternative protein startups raised more than $1 billion in funds from venture capital firms.

    GFI Israel noted that food tech investments in Israel were impacted the least by the market slowdown compared to other tech sectors, with private investments in the tech sector dropping by 42 percent YoY, while investments by venture capital firms in alternative protein startups declined by 20 percent, from $553 million in 2021 to $445 million in 2022.

    Remilk
    Israel’s Remilk is producing dairy via precision fermentation | Courtesy

    Goldstein said that the issue of national food security became more dominant in the food tech industry due to crises in Ukraine, the pandemic, and increasing cases of swine flu. Governments and investors are looking for more resilient and efficient ways to produce proteins, he said. Notable deals in the Israeli plant-based protein sector in 2022 included a $135 million investment in Redefine Meat, a maker of 3D-printed plant-based meat products, and a $124 million investment in Remilk, a developer of animal-free milk and dairy.

    “In order to stay competitive as large global governments invest a lot of money to try to get Israeli startups to open manufacturing sites overseas, we need to move quickly and make sure that we have plans for the academic and startup sector that is experiencing difficulties given macroeconomic conditions, and that we have a plan for industrial incentives and regulation,” Goldstein said. “Those are the four pillars that the government must address in the coming months.”

    Goldstein says the Israeli government could offer state-backed loans to get startups in the sector up and running. “That would allow the startups to overcome the relative shortage in venture capital-backed investments in today’s market conditions,” he said.

    The post Investments In Early-Stage Israeli Alt Protein Companies Grew 130% Between 2021-2022: Report appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 4 Mins Read

    According to new data, year-on-year funding for alternative proteins across Asia Pacific has increased by 43% and shows strong growth across all sector verticals from cultivated to plant-based to fermentation.

    Encouraging growth across the APAC alt protein sector

    The Good Food Institute Asia Pacific (GFI APAC), a leading regional alternative protein non-profit think tank based in Singapore, has crunched the 2022 funding numbers from Pitchbook Data and has found that total investments into the alternative protein sector in the region went up by 43 percent, from $392 million to $562 million. 

    Plant-based food funding rose by 30 percent, from $287 million to $372 million, in large part due to Singaporean startup TiNDLE’s record-breaking Series A round. Precision fermentation and other fermentation investments went up by 67 percent, from $57 million to $95 million with Chinese company Changing Biotech coming out of stealth last August. Cultivated meat, dairy and seafood tech companies saw the biggest growth: 96 percent, from $48 million to $95 million, with Australia-based Vow breaking records with its Series A. One notable change is the classification of Singapore startup TurtleTree, which was considered cultivated in 2021 and is now being treated as a fermentation company.

    On the deal count front, numbers are slightly up since 2021 for fermentation (from 9 to 14) and cultivated food (19 to 20), while plant-based saw a small dip (from 38 to 33). Overall, GFI APAC notes that the funding growth is “broad and deep, not isolated to a single country or company.”

    According to Mirte Gosker, GFI APAC managing director, “building a more secure, sustainable, and just food system is not merely a choice in Asia—it’s a necessity. Conventional animal agriculture is ill-equipped to handle the escalating pressures of skyrocketing protein demand, increased climate disruption, land and water scarcity, and threats of viral outbreaks.”

    Source: GFI APAC

    China and Singapore are alt protein funding hotspots

    GFI APAC highlights two countries in particular where funding growth is strongest: Singapore and China.

    Singapore, which the report calls out as “the only country on Earth where products from all three pillars of alternative proteins are approved for commercial sale”, saw total investments in alternative protein double, from $85 million in 2021 to $170 million in 2022.

    2022 was a big year for alternative proteins in China too. In January, cultivated meat was included in the Ministry of Agriculture and Rural Affairs five-year agricultural plan for the first time, and President Xi Jinping referred to alternative proteins as key for national food security in a March speech. Perhaps as a result of this, alt protein investments showcased significant growth, funding between 2021 and 2022 rose 6x, from $24 million to $152 million.

    GFI APAC underscores the link between public government support towards future food technologies and funding in the space.

    According to Matthew Spence, managing director and global head of venture capital banking at Barclays, “Deep institutional investments from sovereign wealth funds, pension funds, and creative capital sources are key to propelling the global alternative protein sector forward and sustaining a building boom big enough to meet this moment.”

    Source: GFI APAC

    APAC funding is outpacing the global industry

    Globally, venture funding is down across all sectors and food is no different. Rising inflation, supply chain disruptions, an energy crunch, and the Russia-Ukraine war have affected the food sector, both regionally and across the globe. Raw material and ingredients prices are up, as are the costs of production, transportation and distribution.

    Investors are understandably cautious and increasingly conservative, and much of the food tech funding froth of 2020 and 2021 has dissipated in terms of deal count, deal size and valuations. According to GFI APAC, worldwide alternative protein investments are down 76%, from $5.1 billion in 2021 to $2.9 billion in 2022.

    Notwithstanding all this, GFI APAC says investors see the bigger picture, citing a survey showing that 99 percent of participants are optimistic about the long-term potential of the alternative protein industry with 87 percent planning to make investments in the sector in 2023.

    Source: GFI APAC

    The data also shows that APAC is growing in importance comparatively. 2022 marked the first time that alternative protein investments from outside North America accounted for the majority share of the global total with Asia exhibiting the most growth at 43 percent, compared to 24 percent for Europe and a 63 percent decrease in North America.

    As I wrote about Green Queen‘s APAC Alternative Protein Industry Report 2022, regional startups “have been going from strength to strength, hitting major milestones, attracting significant government support and raising record funding rounds.” I further called out the need for diversity and broader representation in media. “Our report illustrates the importance of reporting and media representation. Western-centric media would have you believe that alternative protein is an industry in trouble. In reality, the sector is headed for boom times in Asia and beyond.”

    As Gosker says, “with the global economic downturn starting to make deals more affordable, there is a huge opportunity for forward-thinking investors to reap rewards as Asia’s food future evolves.”

    The post Investments into Asia-Pacific Alt Protein Startups Up 43% Says New Report appeared first on Green Queen.

    This post was originally published on Green Queen.

  • Mirai Foods' cultivated tenderloin | Courtesy
    3 Mins Read

    Mirai Foods, the Switzerland-based food tech startup working on cultivated meat, says it has achieved a breakthrough with the first tenderloin steak grown from cells.

    Mirai Food’s achievement comes by way of a natural cell process that allows for tissue cultivation that can mimic conventional meat. It’s dubbed the tech, which it’s filed three patents on, “Fibration Technology.”

    Cultivated filet

    “Other types of meat can already be produced in the lab,” Christoph Mayr, CEO and co-founder of Mirai Foods, said in a statement. “A fillet steak is the ultimate challenge: it consists of different cell types, which — if combined correctly — result in a complex meat structure,” Mayr says.

    “This structuring process is technologically challenging, making steaks extremely difficult to produce. That’s why Mirai Foods is taking an important step towards sustainable meat with the first cultivated beef tenderloin steak.”

    The Mirai Foods ‘Rocket’ bioreactor. | Courtesy

    The steak was made in Mirai Foods’ in-house developed bioreactor, dubbed “The Rocket”. Mirai says the steak is made with long, fully mature cultivated muscle fibers, which are then combined by enzymes and supplemented with cultivated fat tissue. The process requires five days in a bioreactor, Mirai says, and then “a tenderloin centerpiece is complete, from which steaks of almost any thickness can be cut.”

    “We have filed three international patents for this key technology,” Suman Das, CSO and co-founder of Mirai Foods, said. “We can deliver a real alternative to conventional meat: Using our technology, one can prepare and eat a real steak — and know that no animal had to die for it and the climate is not harmed. Nutrition is a huge lever for greater climate protection and animal welfare: demand for meat is expected to double by 2050; conventional methods of meat production cannot meet this demand at all, and certainly not in a sustainable way.”

    Whole-cut cultivated meat

    Mirai is building on the industry’s increasing efforts to produce whole cuts of meat through cultivation; the majority of products thus far have more resembled mince for use in burgers and nuggets. But in 2023 alone, U.K.-based BSF Enterprises debuted a whole-cultivated pork loin, and researchers in Japan say they’ve also developed a whole-cut steak from cultured cells.

    Mirai Foods; Founder Christoph Mayr and Suman Das with Cows
    Mirai Foods; Founder Christoph Mayr and Suman Das with Cows | Courtesy

    According to Mirai, it’s also one of just a few cultivated meat companies in the world capable of making the meat without the use of genetic engineering — a controversial tech most known for its link with seeds engineered to withstand heavy applications of herbicides. GMOs are heavily restricted in the E.U., and Mirai says the absence of the tech in its meat is geared toward the preferences of European consumers “while maintaining the highest standards of taste, quality, and health.”

    Mirai Foods’ tenderloin debut comes as Zürich-based food and meat producer Angst AG has joined the company along with several other investors. Angst AG is expected to bring Mirai’s cultivated meat into its range of offerings once the tech has earned regulatory approval. Mirai, which launched in 2019, has raised more than $5 million in funding in a 2021 Seed round.

    The post Swiss Start-Up Mirai Foods Debuts the World’s First Cultivated Tenderloin Steak appeared first on Green Queen.

    This post was originally published on Green Queen.

  • tissen bio farm meat
    3 Mins Read

    Cultivated meat industry stakeholders in South Korea, including manufacturers, academia, and several city and provincial governments are working to advance cellular agriculture.

    The memo of understanding (MOU) was led by South Korea’s North Gyeongsang Province (Gyeongsangbuk-do) and 28 signatories including city governments (Pohang-si, Gyeongsan-si, Gumi-si, Uiseong-gun), universities (POSTECH, Yeungnam University), research and technology institutions (Korea Food Research Institute, Gyeongbuk Technopark, Pohang Technopark), and corporations including cultivated meat startup TissenBioFarm, health food manufacturer Ildong Foodis, and functional food ingredients developer Neo-Cremar. 

    Cellular ag hubs across South Korea

    The MOU signals the formation of a cellular agriculture cluster across the country with the goal of addressing climate and food crises, the groups said.

    “We are working on groundbreaking technologies to overcome key challenges in the cultivated meat field,” TissenBioFarm CEO Wonil Han said in a statement. “Once it is done, South Korea will be a global game changer in the field.”

    TissenBioFarm has closely worked with POSTECH, North Gyeongsang Province, the city of Pohang, and the country of Uiseong in efforts to make the region a leader in cellular agriculture.

    TissenBioFarm is developing cultivated meat in South Korea | Courtesy

    The new cluster will focus on cellular agriculture research efforts in South Korea’s southern region. the MOU points to the development of a regulation-free zone to be formed in Uiseong where companies can showcase proof-of-concept. Uiseong will build an industrial complex with facilities ideal for cultivated meat research and production, it says.

    At Yeungnum University in the city of Gyeongsan, an international cell culture research facility will explore culture media, equipment, and systems for developing cultivated meat.

    In Pohang, which already has an established biotech infrastructure, the city will make a test region for research and development, prototyping, and production certification that can support the commercialization of both cultivated meat and artificial organs.

    Gumi will also develop a strategic base to support the advancement of cultivated meat. The city says it will build a branch of the Korea Food Research Institute to support food industrialization.

    Cultivated meat advancements

    Last September, TissenBioFarm raised $1.6 million in a pre-Series A funding round. The company has developed three bio-based inks it says are capable of being mass-produced for about $0.33 per 100 grams. The company says the inks can be used in both cultivated meat and plant-based meat.

    Han says that the technologies will provide high-quality cultured meat that is “competitive in taste, nutrition, sensory, and price in the near future.” 

    Cellmeat’s Cultivated Dokdo Shrimp

    Last April, the South Korean startup CellMEAT, secured $8.1 million in a Series A for its cell-based shrimp. The company also developed its own alternative to the controversial media, fetal bovine serum.

    The post 28 of South Korea’s Cultivated Meat Stakeholders Sign MOU to Advance the Industry appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 3 Mins Read

    University of Tokyo professor Shoji Takeuchi and his colleagues say they have succeeded in producing the world’s first cultivated cubed steak.

    The diced steak was first produced in 2019, when Takeuchi and his team produced a three-dimensional muscle tissue measuring about a cubic centimeter, which the team says can grow to larger cuts. Currently, most cultivated meat is minced, but the majority of animal meat sales are whole cuts.

    Cultivated whole cuts

    “Most startup companies are thinking of ways to commercialize lab-grown meat quickly,” Takeuchi told Japan Times in a recent interview. Much of that meat is being produced as chicken nuggets or hamburgers.

    “What we are trying to create, on the other hand, is a beefsteak, a chunk of beef, where muscle fibers are neatly aligned in parallel position. They can twitch like real muscles when stimulated by electricity. Few people in the world are thinking of creating such meat,” he said.

    cow
    Courtesy Flash Dantz via Pexels

    But the tech is still a long way off from marketable, Takeuchi said.

    “Although we extracted cells from cattle, cultured them and recreated cattle tissues, what we got in the end didn’t taste like beef, unfortunately,” he said. “Something was lost in the process. If we could find out what that is by reviewing the process and fixing it so (cultured meat) tastes like real beef, then we can determine from which point it starts tasting like beef. That would allow us to quantify taste.

    “In the future, we may be able to design the meat we consume, to create meat that perhaps tastes better than real meat. We don’t know if we can do that at this point, but we may be able to.”

    Cultivated meat demand

    The food industry is ready for the tech, even if not yet perfected. Japan’s Nissin Foods Group, the parent company to the leading Cup Noodle ramen brand, began supporting Takeuchi’s research in 2017.

    The cultivated meat sector has raised nearly $2 billion in investments globally, according to data collected by the industry think tank, the Good Food Institute. That’s with Singapore currently the only country to have approved the tech for sale and consumption.

    But other approvals are expected soon. Late last year, the U.S. granted GRAS status to Upside Foods for its cultivated chicken. It must now earn approval from the USDA before it can be sold in the U.S.

    3D Bio-Tissues steak
    3D Bio-Tissues has created the world’s first cultivated pork steak | Courtesy Kenn Reay Photography

    The steak announcement comes just days after U.K.-based BSF Enterprise, a biotech-focused investment company, said its subsidiary 3D Bio-Tissues produced the first cultivated steak in the U.K. made from pork cells. 

    Whole cuts are the holy grail for cultivated meat as well as plant-based meat. Toronto’s New School Foods recently debuted its whole-cut plant-based salmon.

    “The next frontier of meat alternatives is whole cuts,” Chris Bryson, CEO and founder of New School Foods, said in a statement. He says whole cuts represent the majority of animal meat sales, a challenge with two heavily connected issues: “the quality of the meat alternatives in-market and the limited toolkit our industry uses to produce them,” he said.

    “What’s generally available for consumers now are rubbery, ground, pre-cooked products that will not convince the average customer to change their lifelong habits.”

    The post Japan Researchers Create Cultivated ‘Whole’ Steak Cube appeared first on Green Queen.

    This post was originally published on Green Queen.

  • 3D Bio-Tissues steak

    2 Mins Read

    BSF Enterprise, a biotech-focused investment company, says its subsidiary 3D Bio-Tissues has produced the first cultivated steak in the U.K. made from pork cells.

    The first cultivated pork cutlet was made with 3D Bio-Tissues’ (3DBT) serum-free and animal-free cell booster, named City-mix. The result “exceeded expectations in appearance, taste and texture,” the company said. The 3DBT team cooked and ate the filet.

    Cultivated pork filet

    The company says the pork filet is a world’s first for cultivated meat; while a number of companies have developed cultivated pork, much of that has been mince.

    “This is a significant scientific breakthrough which has very positive implications not just for BSF and 3DBT but also for the U.K. and the cultivated meat industry as a whole,” 3DBT CEO Che Connon said in a statement.

    “We are absolutely delighted with the look, taste and texture of our cultivated pork, which is the first time we have fully sampled our product,” Connon said. “Our cruelty-free fillet has exceeded our expectations in all respects, and we are extremely excited about the technological progress we are making and the impact this could have upon our industry.”

    3DBT used pork cells to produce the 3.5-inch by 1.5-inch steak, similar to a typical cut of meat.

    City-mix growth serum

    The company is using City-mix, a lower-cost growth factor that can increase yield without the need for animal-based fetal bovine serum. 3DBT says City-mix is a critical IP component, “providing clear competitive differentiation and world-leading technology.”

    “City-mix, our serum free media in which we cultivated the fillet, is helping to greatly reduce the cost of cultivated meat such that it may become economically viable in the near future,” Connon said.

    3D Bio-Tissues cultivated pork
    Left to right: Dr Craig Stamp, Dr Che Connon and Dr Ricardo Gouveia of 3D Bio-Tissues (3DBT) taste the cultivated pork | Courtesy Kenn Reay Photography

    “At the same time our ‘structure without scaffold’ technology is helping to make cultivated meat that more closely resembles traditional meat in every respect, without the need for plant-based additives,” Connon said. “We look forward to taking the findings through to the next stage of development, focused on producing a chef-ready product for public consumption.”

    According to the testers, the raw steak showed visible meat fibers and structural integrity similar to conventional meat in consistency, elasticity, color, and texture. The cooking process mimicked conventional meat as well: shrinkage, searing, browning, charring, and crisping, with aromas identical to conventional pork. 3DBT says the taste and texture of the final product were indistinguishable from pork.

    The post The First Cultivated Pork Filet Debuts In the U.K. appeared first on Green Queen.