{"id":56836,"date":"2021-02-28T01:27:26","date_gmt":"2021-02-28T01:27:26","guid":{"rendered":"https:\/\/www.factcheck.org\/?p=198208"},"modified":"2021-02-28T01:27:26","modified_gmt":"2021-02-28T01:27:26","slug":"a-guide-to-johnson-johnsons-covid-19-vaccine","status":"publish","type":"post","link":"https:\/\/radiofree.asia\/2021\/02\/28\/a-guide-to-johnson-johnsons-covid-19-vaccine\/","title":{"rendered":"A Guide to Johnson & Johnson\u2019s COVID-19 Vaccine"},"content":{"rendered":"
The Johnson & Johnson vaccine is the third COVID-19 vaccine to be authorized by the Food and Drug Administration. Here, we give a rundown of basic facts about the vaccine and an overview of how it works.<\/span><\/p>\n Vaccine name:<\/b> Ad26.COV2.S<\/span><\/p>\n Design type:<\/b> Adenovirus viral vector\u00a0<\/span><\/p>\n Dose number:<\/b> 1 dose<\/span><\/p>\n Efficacy:<\/b> Overall, 66.1% efficacy<\/a> in preventing moderate to severe COVID-19 in adults 28 days or more after vaccination, but efficacy was higher in the U.S. population (72% efficacy in preventing moderate to severe COVID-19 and 85.9% efficacy in preventing severe or critical COVID-19) than in South Africa (64% and 81.7% efficacy in preventing moderate to severe or severe\/critical disease, respectively), where a new strain of coronavirus emerged.<\/span><\/p>\n Safety:<\/b> No serious safety concerns reported. The shot, however, did elicit temporary side effects in some recipients, including pain at the injection site, headache, fatigue, and muscle pain or ache.\u00a0<\/span><\/p>\n Expected dose availability:<\/b> Nearly 4 million<\/a> available immediately in the U.S. upon FDA authorization; 20 million<\/a> by the end of March and 100 million by the end of June<\/span><\/p>\n Expected timeline:<\/b> On DATE<\/strong>, the FDA authorized the vaccine for emergency use in adults age 18 and older.\u00a0<\/span><\/p>\n Operation Warp Speed involvement:<\/b> The U.S. government provided<\/a> about $1 billion for clinical trials and vaccine development. It spent<\/a> another $1 billion for vaccine manufacturing, contracting for 100 million doses with an option to purchase up to another 200 million.\u00a0<\/span><\/p>\n Storage considerations:<\/b> normal refrigerator temperature (36\u00b0F to 46\u00b0F) for at least three months; -13\u00b0F to 5\u00b0F for long-term storage<\/span><\/p>\n More than two months after its last COVID-19 vaccine authorization, the FDA authorized<\/a> for emergency use a one-shot vaccine from Janssen Biotech Inc., a Johnson & Johnson pharmaceutical company, on Feb. 27.<\/p>\n <\/a>Unlike the Pfizer\/BioNTech<\/a> and Moderna<\/a> vaccines, which use an mRNA design, the Johnson & Johnson shot uses a harmless adenovirus — a type of virus that typically causes the common cold — modified with the genetic material for SARS-CoV-2 to trigger an immune response. The Johnson & Johnson vaccine has the advantages of being one shot, not two, and being stored at regular refrigeration temperatures for up to three months. The Pfizer and Moderna two-shot vaccines can only be kept at refrigerator temperatures for five or 30 days, respectively.<\/p>\n Johnson & Johnson submitted its request for emergency use authorization on Feb. 4. An external panel advising the FDA met on Feb. 26, and voted unanimously<\/a> (22 to 0) that \u201cbased on the totality of scientific evidence available … the benefits of the Janssen COVID-19 Vaccine outweigh its risks for use in individuals 18 years of age and older.” The FDA then authorized the vaccine for emergency use the following day.<\/p>\n The design is different from the mRNA vaccines authorized in December, but all of the vaccines fundamentally work in the same way: They trigger an immune response<\/span><\/a>\u00a0against the SARS-CoV-2 virus\u2019s spike protein, which sits on the surface of the virus and is what the virus uses to enter cells.<\/span><\/p>\nQuick Summary<\/span><\/h2>\n
Johnson & Johnson Q&A<\/h2>\n
What is in the vaccine and how does it work?<\/h2>\n